ACE Inhibitors

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URL of this page: http://www.nlm.nih.gov/medlineplus/ency/patientinstructions/000087.htm
ACE inhibitors
Angiotensin-converting enzyme (ACE) inhibitors are medicines. They treat heart, blood vessel, and kidney problems.
How ACE Inhibitors HeIp You
ACE inhibitors are used to treat heart disease. These medicines make your heart work less hard by lowering your
blood pressure. This keeps some kinds of heart disease from getting worse. Most people who have heart failure take
these medicines.
These medicines treat high blood pressure, strokes, or heart attacks. They may help lower your risk for stroke or
heart attack.
They also are used to treat diabetes and kidney problems. This can help keep your kidneys from getting worse. Ìf you
have these problems, ask your doctor if you should be taking these medicines.
Types of ACE Inhibitors
There are many different names and brands of ACE inhibitors. Most work as well as another. Side effects may be
different for different ones.
Taking Your ACE Inhibitors
ACE inhibitors are pills that you take by mouth. Take all of your medicines as your doctor told you to. Try to take them
at the same time, or times, each day. Do not stop taking your medicines without talking with your doctor first.
Follow up with your doctor regularly. Your doctor will check your blood pressure. Your doctor will also do blood tests to
make sure the medicines are working properly. Your doctor may change your dose from time to time.
Plan ahead so that you do not run out of medicine. Make sure you have enough with you when you travel.
Other important tips are:
Before taking ibuprofen (Advil, Motrin) or aspirin, talk to your doctor.
Tell your doctor what other medicines you are taking. This includes anything you bought without a prescription,
diuretics (water pills), potassium pills, or herbal or dietary supplements.
Do not take ACE inhibitors if you are pregnant or breastfeeding. Do not take these medicines if you are planning
to become pregnant. Call your doctor if you become pregnant when you are taking these medicines.
Side Effects
Side effects from ACE inhibitors are rare.
You may have a dry cough. This may go away after a while. Ìf it does not, tell your doctor. Sometimes reducing your
dose helps, but sometimes your doctor will switch you to a different medication. Do not lower your dose without talking
with your doctor first.
You may feel dizzy or lightheaded when you start taking these medicines, or if your doctor increases your dose.
Standing up slowly from a chair or your bed may help. Ìf you have a fainting spell, call your doctor right away.
Some other side effects are:
ACE inhibitors: MedlinePlus Medical Encyclopedia http://www.nlm.nih.gov/medlineplus/ency/patientinstructions/000087.htm
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Headache
Feeling tired
Loss of appetite
Upset stomach
Diarrhea
Numbness
Fever
Skin rashes or blisters
Joint pain
Ìf your tongue or lips swell, call your doctor right away, or go to the emergency room. You may be having a serious
allergic reaction to the medicine. This is very rare.
When to CaII the Doctor
Call your doctor if you are having any of the side effects above. Also call your doctor if you are having other unusual
symptoms.
AIternate Names
Angiotensin-converting enzyme inhibitors
References
Mant J, Al-Mohammad A, Swain S, Laram e P; Guideline Development Group. Management of chronic heart failure in
adults: synopsis of the National Ìnstitute For Health and Clinical Excellence guideline. Ann Ìntern Med. 2011
Aug16;155(4):252-9.
Greenberg B and Kahn AM. Clinical assessment of heart failure. Ìn: Bonow RO, Mann DL, Zipes DP, Libby P, eds.
Braunwald'sHeart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Saunders; 2011:chap 26.
Gaziano M, Ridker PM, Libby P. Primary and secondary prevention of coronary heart disease. Ìn: Bonow RO, Mann
DL, Zipes DP, Libby P, eds. Braunwald'sHeart Disease: A Textbook of Cardiovascular Medicine. 9th ed.Saunders;
2011:chap 49.
Riegel B, Moser DK, Anker SD, et al; American Heart Association Council on Cardiovascular Nursing; American Heart
Association Council on Clinical Cardiology; American Heart Association Council on Nutrition, PhysicalActivity, and
Metabolism; American Heart Association Ìnterdisciplinary Council on Quality of Care and Outcomes Research. State of
the science: promoting self-care in persons with heart failure: a scientific statement from the American Heart
Association. Circulation. 2009 Sep 22;120(12):1141-63.
Jessup M, Abraham WT, Casey DE, Feldman AM, Francis GS, Ganiats TG, et al. 2009 focused update: ACCF/AHA
Guidelines for the Diagnosis and Management of Heart Failure in Adults: a report of the American College of
Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: developed in collaboration with
the Ìnternational Society for Heart and Lung Transplantation. Circulation. 2009 Apr 14;119(14):1977-2016. Epub 2009
Mar 26.
Update Date: 8/5/2012
Updated by: Michael A. Chen, MD, PhD, Assistant Professor of Medicine, Division of Cardiology, Harborview Medical
Center, University of Washington Medical School, Seattle, Washington. Also reviewed by David Zieve, MD, MHA,
Medical Director, A.D.A.M. Health Solutions, Ebix, Ìnc.
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