Gluten-Casein Peptides Test

Published on July 2016 | Categories: Documents | Downloads: 37 | Comments: 0 | Views: 315
of 2
Download PDF   Embed   Report

Gluten-Casein Peptides Test

Comments

Content

Gluten / Casein Peptides Test
Testing for food sensitivities is the first step in developing an integrated treatment plan
Benefits of Testing The Great Plains Laboratory, Inc. (GPL) offers the Gluten/Casein Peptides Test which can help determine the inability to digest wheat, rye, barley, and milk proteins. These undigested proteins called peptides are associated with GI, neurological, and neuro-developmental disorders. The Gluten/Casein Peptides Test measures levels of both casomporhin and gliadorphin. GPL’s simple and accurate Gluten/ Casein Peptides Test uses the ELISA method, which is highly specific to the nanogram level, or one-billionth of a gram. To accomplish this, casomorphin and gliadorphin are custom-synthesized to be able to define the very sensitive standard curve that is required. This test is a very useful tool in determining whether dietary modifications should be part of an integrated treatment plan, or whether the diet should be maintained if it is currently used. It is also important to identify potential symptoms of yeast and fungal overgrowth. Digestive enzymes may improve these symptoms especially after accidental diet infractions. The Gluten/Casein Peptides Test determines sensitivities even when a patient has no IgE or IgG allergic reactions to these foods. If either of the peptide results is abnormal, both gluten (from gliadorphin) and casein (from casomorphin) should be eliminated. If you suspect that you or your child has abnormal levels of peptides, contact GPL to obtain a test kit. Casomorphin is one of the peptides produced from casein, a major protein in all mammalian milk. Digestion of gluten in wheat also produces peptides of similar size, one of which is gliadorphin. Because of structural similarity, these peptides are presumed to affect the brain similarly. Both casomorphin and gliadorphin are 7-amino acid peptides with a beginning N-terminal sequence tyr-pro (for tyrosine and proline) with an additional pro in positions 4 and 6 (see below). Matching amino acid residues are bolded.
1 2 3 4 5 6 7

Elimination Diet How does the gluten-free, casein-free (GFCF) diet work, and who might benefit from undertaking such radical changes in eating? Some individuals have difficulty breaking down peptides, small protein fragments that engage in cell-to-cell signaling and interact with opiate receptors. Because the diet is so demanding, it is ideal to be certain that someone has the peptide problem before starting the diet. This is why testing for peptides can be very helpful. An enzyme nicknamed DPPIV is required to break down the peptides but can be inhibited by yeast by-products and mercury exposure. Although DDPIV containing enzymes are available and are very useful, the diet alone is suggested for the initial phase. A gradual approach to the GFCF diet usually works best. Because casein and gluten peptides function as opiates, a withdrawal reaction similar to that of a drug addict may occur when these foods are removed from the diet.

Casomorphin: tyr-pro-phe-pro-gly-pro-ile Gliadorphin: tyr-pro-gln-pro-gln-pro-phe

Several studies have linked high levels of opiate peptides in urine with gastrointestinal (GI), neurological, and neuro-developmental disorders. Negative symptoms from excess casein and gluten peptides range from constipation to drowsiness and poor concentration. Other symptoms include cravings for wheat and dairy products, and discomfort after eating them.

Gluten/Casein Peptides Test
Gluten-Casein Peptides Test Brochure 5/3/11

Page 1

Specimen Requirements 5 mL of urine is the absolute minimum required. 10 mL of urine is preferred. The patient must discontinue consumption of soy and soy proteins one week prior to sample collection. Soy bean oil and soy lecithin are considered acceptable. First morning urine before food and drink is preferred. Testing Procedure 1. Contact The Great Plains Laboratory, Inc. via phone, fax, e-mail, or on our website to order a test kit. 2. Fill out the Test Requisition Form, have this form signed by a medical practitioner. 3. Indicate the payment method or insurance information on the Test Requisition Form. 4. Follow the instructions to collect the sample. 5. Send the sample with the paperwork in the pre-paid express overnight envelope included in the test kit (shipping cost is included in the price for U.S. clients). 6. The results will be mailed with a detailed explanation to the patient and medical practitioner in approximately one to three weeks after receiving your sample, unless the practitioner has specified otherwise. 7. A free phone consultation with our nutritional consultant is available to practitioners and patients upon request. • • • • • • • • • • • • • • • • •
William Shaw, Ph.D Director 11813 W. 77th Street, Lenexa, KS 66214 (913) 341-8949 Fax (913) 341-6207

Recommended for the following disorders: AD(H)D AIDS Alzheimer’s Disease Arthritis Autism Spectrum Disorders Chronic Fatigue Syndrome Colitis & Crohn’s Disease Depression Diarrhea/Constipation Down Syndrome Fibromyalgia Movement Disorders Multiple Sclerosis OCD Psychoses Schizophrenia Tic Disorder Tourette Syndrome

The Great Plains Laboratory, Inc.



Gluten/Casein Peptides Test
Gluten-Casein Peptides Test Brochure 5/3/11

Page 2

Sponsor Documents

Or use your account on DocShare.tips

Hide

Forgot your password?

Or register your new account on DocShare.tips

Hide

Lost your password? Please enter your email address. You will receive a link to create a new password.

Back to log-in

Close