MS Contin,
Kadian,
Avinza,
Oramorph,
MSIR,
Roxonal,
OxyIR,
OxyContin
+IB:Ibudone,
Reprexian,
Vicoprofen
Action
Indication
Depresses
pain
impulse
transmissi
on at SC
by
interactin
g with
opioid
receptors;
decreases
cough
reflex, GI
motility
Mild to
moderate
+aspirin:
Percodon,
endodan
+acetaminophe DepoDur:IC
n:Duocet
P and
Norco, Vicodin
increase
CNS
depression
Acts directly on Depresses
the cough
pain
center in the
impulse
medulla to
transmissio
suppress
n at the SC
cough; binds to level by
opiate
interacting
receptors in
with opioid
CNS to reduce
receptors
pain
Compete with opioids for CNS
receptor site
Complete or partial reversal of
opioid induced respiratory
depression
Compete with opioids for CNS
receptor site
Used as an adjunct for the
maintenance of an opioid free
state for addicts
Opioid overdose
Adjunct to psychosocial
Indication
treatments of alcoholism
Contraindication/caution
Hypersensitivity
Side Effect
Does NOT cause respiratory
depression or produce analgesia
Withdrawal syndrome:Raised or
lower blood pressure, dyshythias,
pulmonary edema, withdrawal
Reversal of postop opioid induced
respiratory depression
Hypersensitivity, hepatitis, severe
liver dysfunction
Nausea and tachycardia
Nervousness headache N V
pulmonary edema, withdrawal