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Nursing notes

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Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of

enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to

increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:

Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on

anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline

information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on

Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)

Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued

therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy

Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.

The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during

Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection

Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug

Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild

thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy
Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin
Anticoagulation therapy No IM drugs during
Anticoagulants are antithrombotic drugs\
complete laboratory tests before the start of anticoagulant therapy to establish baseline
information about the patient's coagulation status and to serve as a reference for
comparison during therapy.
The Institute for Safe Medication Practices recommends completing a baseline
hematocrit, hemoglobin, serum creatinine, and platelet count before starting patients on
anticoagulant therapy

Types of anticoagulant drugs:
Unfractionated heparinDoes not dissolve existing thrombus, but prevents the
extension of the thrombus and more thrombi from forming. May cause mild
thrombocytopenia (Appears on 4th day of therapy and resolves with continued
therapy. Heparin-induced thrombocytopenia occurs on 8th day and may lead to
increased resistance to heparin therapy. Protamine sulfate is antidote. Due to
short half life overdose can be treated by withdrawing the drug
Low-molecular-weight heparin (Enoxaparin, Dalteparin, and Tinzaparin)
Enoxaparin (Lovenox) Antidote Protamine sulfate 1mg for each mg of
enoxaparin by slow IV injection
Warfarin (Coumadin)Antidote Vitamin K (Avoid foods high in vitamin K).
Takes 3-5 days to reach effective levels; Usually begun while patient still on
Heparin

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