Noun 1. Seattle - a major port of entry and the largest city in Washington; located in west central Washington on the protected waters of Puget Sound with the snow-capped peaks of the Cascade Range and Mount Ranier visible to the south and east; an aerospace and computer center; site of the University of Washington Space Needle - a tower 605 feet tall in Seattle; a tourist attraction University of Washington - a university in Seattle, Washington Evergreen State, WA, Washington - a state in northwestern United States on the Pacific