Tablet

Tablet
Lecture notes
Tablet?
Solid dosage form
Compact
From the powders / granules which can be
compressed or molded
Ìt contains one or more pharmacological active
ingredients
Various shape and size
hy tablets ?
Ensure the more precise dose in each tablet,
compared to powders
Provide better physical and chemical stability
smaller contact area to atmosphere
Can be modified in terms of release of the drug
Available in large-scale manufacturing
imitation of application,
in general.
An orally disintegrating tablet is not a
choice for patients who find difficulties in
swallowing quite large volume of matters
Ìt needs disintegrating time, compared to
solution
Types of tablet
ased on method of
manufacturing
Compressed tablets
Direct compression
et granulation
Dry granulation
Molded tablets
ased on disintegration and
release type
Fast dissolving tablets/rapidly dissolving
tablets/instant-release tablets
Orally disintegrating tablets / immediate
release tablets
Sustained/extended release tablets
Delayed release tablets
ased on location of
administration
uccal tablets
Sublingual tablets
Oral tablets
Vaginal tablets
ased on type of coating
Sugar coated tablets / dragee
Film coated tablets
Enteric coated tablets
Others.
Effervescent tablets
Multiple compressed tablets
Chewable tablets
ozenges / troches
Dispensing tablets
Tablet composition
Active ingredients
inders mucilage, sol. gelatin 10%
Disintegrating agent Starch RX,
ubricants Mg stearic
Fillers lactose
(Flavoring agents)
(Coloring agents)
(Coating agents)
Tablet evaluation
Visual appearance smoothness of
surface, shape, colour
Dimension thickness, width
eight variation
Content uniformity
Tablet hardness and friability
Tablet disintegration time
Tablet dissolution
425,8843 kepada pasien
ika pasien mengalami kesulitan dalam
menelan tablet, pilihkan alternatif
sediaan lain
Saat akan menelan tablet, arahkan
pasien meletakkan pada bagian lidah
yang dalam
Arahkan pasien untuk menelannya
dengan air putih secukupnya
Arahkan pasien untuk menyimpan sisa
obat dengan benar, jauh dari jangkauan
anak-anak