of 6

Tuberculosis Complications

Published on December 2017 | Categories: Documents | Downloads: 32 | Comments: 0
324 views

Comments

Content

Tuberculosis Complications and Prognosis

Pulmonary Complications Anatomic Site

Complications

Lung parenchyma

• • • • •

Tuberculoma Residual cavitation Aspergilloma Scarring or fibrosis Obstructive or restrictive ventilatory deficits

Airways

• Bronchiectasis • Tracheobronchial stenosis • Broncholithiasis (calcified mediastinal nodes erode into airways)

Vascular

• Pulmonary or bronchial arteritis or thrombosis • Rasmussen pseudoaneurysm (cause massive hemoptysis – rare)

Pleural

• Chronic empyema • Bronchopleural fistula • Pneumothorax

Extrapulmonary Complications Anatomic Site

Complications

Mediastinal/Cardiac

• • • •

Esophagobronchial fistula TB pericarditis Constrictive pericarditis Cardiac tamponade

CNS

• TB meningitis • Tuberculomas – focal neurologic deficits/seizures • Vasculitis or stroke • Hydrocephalus (more common in children)

Eye

• Posterior or anterior uveitis • Choroiditis • Optic neuropathy

Genitourinary

• • • •

Renal TB Uretral stenosis Hydronephrosis Prostatic abscess

Extrapulmonary Complications cont. Anatomic Site

Complications

Endocrine/Metabolic

• Adrenal insufficiency • Hypercalcemia

Lymph nodes

• Paradoxical worsening of lymphadenitis • Lymphocutaneous fistulas

Abdomen

• Tuberculous ascites • Peritoneal implants • Granulomatous colitis (may mimic Crohn’s disease) • Pelvic abscess

Bone

• Focal osteomyelitis • Spinal discitis and osteomyelitis (Pott’s disease) • Pathologic fractures

Prognosis  In general, patients treated with TB do well with minimal or no sequelae.  Risk factors for mortality include increased age, delay in diagnosis, extend of TB involvement, the need for mechanical ventilation, and concomitant diagnosis of ESRD, diabetes and immunosuppression esp HIV.  In disseminated TB mortality rate has been reported as high as 38%, and if therapy is delayed for more than 6 weeks, mortality from TB peritonitis approaches 60%.

References  http://ovidsp.tx.ovid.com.ezproxy.lib.monash.edu.au/sp3.16.0a/ovidweb.cgi? WebLinkFrameset=1&S=EBMEFPIKNJDDCHJHNCKKPCOBCIG BAA00&returnUrl=ovidweb.cgi%3f%26Full%2bText%3dL %257cS.sh.22.23%257c0%257c00001432-20141000000002%26S %3dEBMEFPIKNJDDCHJHNCKKPCOBCIGBAA00&directlink=htt p%3a%2f%2fgraphics.tx.ovid.com%2fovftpdfs %2fFPDDNCOBPCJHNJ00%2ffs047%2fovft%2flive %2fgv024%2f00001432%2f00001432-20141000000002.pdf&filename=Complications+of+tuberculosis.&pdf_key=FP DDNCOBPCJHNJ00&pdf_index=/fs047/ovft/live/gv024/00001432/ 00001432-201410000-00002  http://bestpractice.bmj.com.ezproxy.lib.monash.edu.au/bestpractice/monograph/166/follow-up/prognosis.html

Sponsor Documents


Recommended

No recommend documents

Or use your account on DocShare.tips

Hide

Forgot your password?

Or register your new account on DocShare.tips

Hide

Lost your password? Please enter your email address. You will receive a link to create a new password.

Back to log-in

Close