Definition Features Etiology Diagnosis Differential
a chronic organic disorder characterized
by: -impairment of intellectual functions -impairment of memory -deterioration of personality with lack of personal care.
of judgment, impulse control & abstract thinking. Emotional labiality Catastrophic reaction Thought abnormalities- delusions & perseveration. Disorientation in time (place & person in late stage) Neurological signs depending on underlying cause.
developed drug TACRINE HYDROCHLORIDE (COGNEX) Ach concentration by slowing its degeneration.
Multiple cerebral infarction Progressive disruption of brain function Dementia
Abrupt Acute Step
exacerbation due to repeat infarction
ladder pattern of deterioration course
of hypertension or other CVS
H/O stroke or TIAs.
evaluation: -presence of focal neurological signs -insight in to the illness present -emotional lability present.
Treatment of underlying cause prevents further deterioration.
important treatable & reversible cause of dementia. confirmed by lab tests.
treatment can reverse dementia & can lead to complete recovery within 2 years of onset of dementia.
of AIDS patients exhibit triad of COGNITIVE, BEHAVIOURAL & MOTORIC deficits of SUB CORTICAL DEMENTIA type known as ADC.
AIDS virus – neurotropic features Crosses blood brain barrier early in disease Cognitive impairment
Confirmation of disease by: -ELISA -western blot technique
CT scan will show cortical atrophy MRI helpful in detecting white matter lesions.
required: Evidence of decline in both memory & thinking, sufficient to impair personal activities.
to ICD-10,following features are
impairment typically affects registration, storage & retrieval of new information(recent memory). Remote memory may be intact till late stages.
& reasoning capacity impaired
of ideas reduced of clear consciousness of atleast 6 months.
-intellectual impairment is severe enough to interfere with social/occupational functioning SENESENT FORGETFULNESS.