Drugs Contraindicated during Pregnancy/Drugs Safe during Pregnancy

Drugs Contraindicated in Pregnancy: Category B: Antibiotics = Ampicillin/Penicillin /Erythromycin Metronidazol ( Flagyl) = Contraindicated in 1st Trimester Category C: Corticosteroids Chloramphenicol* : Antibiotic ( grey baby syndrome) Sulfonamide (A/b: Sulfa Drugs = begins with “Sulfa”) Sulfonyureas* ( Oral Antidiabetic) Fluoroquinolones = Ciprofloxacin/ Levofloxacin/ Norfloxacin Opioids/Narcotics = Codeine/Oxycodone/Hydrocodone Percocet ( Acetaminophen + Oxycodone) Antifungal = “ Conazole”: Ketoconazole/Miconazole/Tioconazole Nystatin/Griseofulvin Category D: ACE - Inhibitors*: ( “ Pril”) = Enalapril/Lisinopril Beta-Blockers: ( “ Lol”) = Atenolol ( fetal growth retardation) Benzodiazepines*( “Zepam”/”Zolam”) Barbiturates = Phenobarbital Aminocaproic Acid Aminoglycosides* = Gentamycin/Tobramycin/Amikacin ( deafness of fetus) Anticonvulsant * =Carbamazepine ( Tegretol)/ Dilantin ( Phenytoin)/ Valproic Acid ( Depakote) Chemotherapy Drugs ( exc. methotrexate) = Busulfan/Chlorambucil/Cyclophosphamide Lithium* = Manic Stage of Bipolar Disorder NSAIDS* = Contraindicated in 3rd Trimestr ASA (Aspirin)/Indomethacin/Naproxen (Aleve)/Excedrin/Midol “Profen” =Ibuprofen (Advil, Motrin)/Vicoprofen(Hydrocodone + Ib uprofen) “Lac”/”Dac”/”Fenac” = Ketorolac/ Sulindac/Diclofenac “Coxib” = Celecoxib ( Celebrex) Tetracyclines* = Doxycycline ( Vibramycin)/ Minocycline: ( child’s teeth staining ) Thiazides Diuretics = Hydrochlorothiazide ( fetal growth retardation) Thyroid Drugs = PTU ( Propylthiouracil)/ Triiodthyronine/Methimazole Potassium Iodide ( SSKI)/Radioactive Iodine ( cause fetal goiter) Category X: Benzodiazepines* ( “Zepam”/”Zolam”) Oral Contraceptives* ( Birth Control Pills) = All a)COCP: Estrogen-Progesterone/ (Estradiol- Progestin) Combination = the “Pill”: *Alesse/Aviane/Brevicon/Ogestrel/Ortho-Novum/Ovcon/Tri-Cyclen/Triphasil Beyaz/Yasmin/Yaz = Take Orally)/ Nuvaring = Take Intravaginally b)POP: Progesterone Only = “ Mini-Pill” ( must take = at the same time each day) *Depo-Provera ( Medroxyprogesterone) = 3-month shot: Deep IM Gluteal/Deltoid. Micronor ( Norethindrone) = Take Orally Implanon ( Etonogestrel) = Implant Hormone Replacement Therapy* = All (Synthetic Estrogens (Estradiol)/Progesterone s) Estrone/Menest/ Premarin/Cenestin/Ogen = synthetic estrogen Diethylstilbestrol *(DES) = synthetic estrogen, antineoplastic Progestaject/Progestasert/Prometrium = synthetic progesterone Danazol* ( Danocrine)= synthetic testosterone : used to treat endometriosis, fib rocystic breast disease) Finasteride* ( Proscar) = synthetic antiandrogen to treat benign prostatic hyper plasia Mifepristone = synthetic hormone to terminate pregnancy

Misoprostol = prevent & treat nsaids-gastric ulcers Methotrexate = Chemotherapy Raloxifene (Evista) = serm : selective estrogen receptor modulator to prevent os teoporosis in postmenopausal women. Retinoids *: Isotretinone ( Acutane)/Vit.A preparations Ribavirin = Antiviral : for Severe RSV Infection/ Hepatitis C Quinine = Anti-malarial : causes deafness of fetus Statins* ( Lovastatin/Atorvastatin/Simvastatin) Thalidomide ( Thalomid) = used to treat multiple myeloma Warfarin *( Coumadin) = anticoagulant, crosses placenta ( fetal warfarin syndrom e, spontaneous abortion, stillbirth, iugr, blindness, mental retardation) Immunizations Contraindicated = Live Vaccines: MMR, Polio, Chickenpox Immunizations Safe during Pregnancy = Diphtheria/Tetanus Toxoid/Influenza/Hep. B Drugs Safe during Pregnancy: Acetaminophen ( Tylenol) Antacids : Maalox, Mylanta,Pepcid, Zantac Antiemetic: Reglan, Phenergan, Zofran Antihistamines: Claritin, Benadryl, Zyrtec, Allegra Azythromycin ( Zyrthromax) Bisacodyl ( Dulcolax) Cephalosporins: Ancef, Duricef, Keflex, Ceclor, Ceftin Clotrimazole ( Mycelex) Colace ( Docusate) Cough Suppressants : Robitussin ( Guaifenesin) Decongestants: Sudafed Erythromycin Heparin Insulin Levothyroxine ( Synthroid) Methyldopa ( Aldomet) Methamucil Nasal Contestants: Nasonex, Flonase Penicillins ( Amoxicillin, Ampicillin) Simethicone Terbutaline ( Brethine) Yeast : Nystatin, Monistat, Femstat, Terazol, Lotrimin

Drugs that are capable of acting as teratogens include: • ACE (angiotensin converting enzyme) inhibitors • Acne medication: Isotretinoin (ACCUTANE, RETIN-A). • Alcohol -- increases the risk of a stillbirth and the Fetal Alcohol Syndrome. • Androgens (male hormones). • Antibiotics: Tetracycline (ACHROMYCIN), and Doxycycline (VIBRAMYCIN), Streptomy cin. • Quinolones: Ciprofloxacin ( Cipro)/ Floxin (Ofloxacin)/Levaquin ( Levofloxacin) / • Anticoagulant (blood-thinner) Warfarin(COUMADIN). • Anticonvulsants (seizure medications) such as: - Phenytoin (DILATIN), - Valproic acid (DEPAKENE, VALPROTATE), -Trimethadione (TRIDIONE), - Paramethadione (PARADIONE), - Carbamazepine (TEGRETOL). • Anti-depressant drug: Llithium(ESKALITH, LITHOB).

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Antimetabolite/anticancer drugs: Methotrexate (RHEUMATREX) and Aminopterin. Antirheumatic agent and metal-binder (chelator): Penicillamine (CIPRIMENE, DEPEN Antithyroid drugs such as: Thiouracil/propylthiouracil and Carbimazole/methimazole. Cocaine. DES (diethylstilbestrol), a hormone. Thalidomide (THALOMID)