ENDOCRINOLOG
Y
a medical approach to reproductive hormones
DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA IUNIVERSITY OF THE IMMACULATE
BACHELOR OF MEDICAL LABORATORY SCIENCE
PAGUNSAN
CONCEPTION
3
a
bout
TALK
progesteron
LET’S
GROU
P
ENDOCRINOLOG
Y
a medical approach to reproductive hormones
e
UNIVERSITY OF THE IMMACULATE
DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA I
BACHELOR OF MEDICAL LABORATORY SCIENCE
PAGUNSAN
CONCEPTION
ENDOCRINOLOG
PROGESTERONE: the insid
Y
LET’S
Structure and Functions
TALK
Hormone Synthesis
about
progesteron
e
Pathologic condition
Laboratory Test
Treatment and Management
Summary
UNIVERSITY OF THE IMMACULATE
DUMAGPI I EDIT I JARINA I JERUSALEM I LUMAMBAS I MANDAWE I ORDANEZA I
UNIVERSITY
OF THE
IMMACULATE
BACHELOR
OF MEDICAL
LABORATORY
SCIENCE
PAGUNSAN
CONCEPTION
BACHELOR OF MEDICAL LABORATORY SCIENCE
mens
es
FOLLICULAR PHASE
FSH and LH interacts during the
menstrual cycle
FSH is inhibited by high levels of
estrogen; LH is inhibited by low levels of
estrogen
FSH acts on the development of follicle
that will be dominant during the next
cycle
mense
s
Core reaction
cholesterol
testosterone estradiol
progesterone17-hydroxyprogesterone
androstenedione
pregnenolone
17-hydroxypregnenolone
dehydroepiandrosterone
estrone
CORPUS LUTEUM
THECA CELLS
GRANULOSA CELLS
endocytosi
cholesterol
s
Y
Y
Inside the ovar
synthes
is
glucocorticoids
granulosa cell
mineralocorticoid
sgonadal steroid
lipoprotei
n
Enzymatic
reaction
luteinizing
hormone
Cholesterol cleavage enzyme
cholestero
l
3B-hydroxyl-steroiddehydrogenase
pregnenolone
progesterone
Further converted to
other product
Inside the
cell
progesterone
used in the reproductive
system for cell activities
progesterone
Up next
GONADAL STEROID
DISEASES &
DISORDERS
Ms Shaira Edit
Department of Clinical Chemistry
Endocrinology Section