# GECG Curriculum - Biomedical Engineering

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B.E FIRST YEAR
101 - MATHEMATICS
1
2

3

4

5

6

7

Differential Calculus
Successive Differentiation : Leibnitz Theorem, Taylor's And Maclaurin Expansions,
Indeterminate Forms.
Tracing Of Curves ++
Asymptotes (Parallel To Axis And Oblique) Tracing Of Cartesian, Parametric And
Polar Curves.
Partial Differentiation
Partial And Total Differential Coefficient, Euler's Theorem, Transformations,
Geometrical Interpretation Of Partial Derivatives, Tangent Plane And Normal
Line, Jacobeans, Taylor's Expansions For
Two Variables, Errors And
Approximations, Maxima And Minima Of Functions
Of
Two
Variables,
Lagrange's Method Of Undetermined Multipliers To Determine Stationary Values.
Integral Calculus
Reduction Formulae: Beta, Gamma And Error Functions, Elliptic Functions
Application Of Integration : Area Of A Bounded Region, Length Of A Curve,
Volume And Surface Area Of A Solid Of Revolution For Cartesian, Parametric And
Polar Curves.
Multiple Integrals
Double Integral, Change Of Order Of Integration, Transformation Of Variables By
Jacobean Only For Double Integration, Change To Polar Co-Ordinates In Double
Integrals Only. Triple Integral, Application Of Multiple Integration To Find Areas,
Volumes, C.G., M.I. And Mean Values.
Complex Numbers
De Moivre's Theorem And Its Applications, Functions Of Complex Variables
Exponential, Hyperbolic And
Inverse
Hyperbolic Trigonometric And
Logarithmic.
Infinite Series
Definition, Comparison Test, Cauchey's Integral Test, Ratio Test, Root Test,
Leibnitz's Rule For Alternating Series, Power Series, Range Of Convergence,
Uniform Convergence.
Matrix Algebra
Elementry Transformations And Rank, Inverse By Elementry Transformation,
Normal Form Of A Matrix, Consistency Of System Of Linear Equations, Solution
Of Systems Of Equations, Linearly Dependent Vectors In R3, Linear And
Orthogonal Transformations, Eigen Values, Eigen Vectors.

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
Gandhinagar-382028.
Tel: (079)29289540 ; Fax : (079)23243708
Email: [email protected]

8

Differential Equations And Modeling
Modeling Of Engineering System (Leading To Ode Of First Order, First Degree,
Including Orthogonal Trajectories), Exact Differential Equations And Integrating
Factors, Unified Approach To Solve First Order Equations, Linear, Reducible To
Linear, Applications Including Modeling, Solution Of First Order And Higher
Degree Differential Equations (Clairut's Equations Only)

Reference Books
1 Elementary Engineering Mathematics & Higher Engineering Mathematics By B.S.
Grewal (Khanna Publishers, Delhi)
3 Engineering Mathematics I & II By Wartikar & Wartikar (Pune Vidyarthi Griha
Prakashan, Pune)
4 Engineering Mathematics (II) Advanced Engineering Mathematics By H.K. Das (S.
Chand & Co. Ltd., New Delhi)
5 Engineering Mathematics By Vol. I,II & III By Kandaswamy, Thilagavathi And
Gunavathi (S. Chand & Co. Ltd., New Delhi)
6 6. A Text Book Of Engineering Mathmatics By Srivastava And Dhawan
(Dhanpat Rai & Sons, Delhi)
7 Engineering Mathematics Vol. I & II By S.S. Sastry (Phi)
8 A Text Book Of Engineering Mathematics By Bali, Saxena & Iyengar (Laxmi
Publications, New Delhi)
9 Engineering Mathematics I,II(F.E.Sem.I & II) By Kumbhojkar G. V. (C. Jamnadas
& Co., Bombay)

102 OFFICE AUTOMATION
1

Installation & Use Of Single User Operating System
Note: Any Two Widely Used Operating System May Be Used As Examples.
Hardware Requirements For Microsoft Dos And Windows Installation, Ms-Dos
Commands And Programming, Customizing And Configuring Windows, Configuring
The Taskbar, The Start Menu, Using The Windows Interface To Create, Print, And
Store A File Using Explorer, Managing Disk Resources And Utilities, Manage Long
And Short Filenames In A Mixed Environment, Disk Defragmenter, Scan Disk,
Running Applications, Installation Methods, Architecture And Memory, The Memory
Usage Of A Ms-Dos Based Application Operating In Windows.

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Email: [email protected]

2

3

Microsoft Word
Overview Of Microsoft Word, Formatting Text And Documents, Headings, Footers
And Footnotes, Tabs, Tables And Sorting, Working With Graphics, Templates,
Wizards And Sample Documents, Tools – Spell Check, Mail Merge.
Fundamental Of Worksheet Usage
Worksheet Fundamentals, Embedding, Enhancing And Modifying Charted Data,
Formatting Worksheet Data, Producing List Type Information, Customization Of The
User Interface For Optimal Performance, Data Organization, Data Analysis, Data
Manipulation, Data Access, Querying External Database Form Within The
Worksheet, Import And Export Of Data Integration With Other Applications.

4

Microsoft Power Point
Overview Of PowerPoint, Creating And Formatting Presentations, Working With
Text, Working With Graphics.

5

Usage Of Internet
Getting Connected To Internet And Visit Of Popular Web Sites.

Practical and Term work
The practical and Term work will be based on the topics covered in the syllabus.
Minimum 10 experiments should be carried out.
References:
1
2
3
4

Mastering Dos 6.2 – By Robbins(BPB)
Mastering Windows-95 By Coward(BPB)
The Compact Guide To Microsoft Office Professional – Ron Mansfield (BPB)
Books Online By Microsoft
103 - MECHANICS OF SOLIDS

1
2

Introduction : Scaler and Vector Quantities, composition and resolution of vectors,
definition and units of space, time, metal, force, the science of mechanics, SI Units.
Statics: Principles of statics, particle, rigid body, coplanar, concurrent and nonconcurrent parallel and non-parallel forces, composition and resolution of forces,
moment, couples and their properties, combination of coplanar couples and forces,
equilibrant, equilibrium, free body diagrams, analytical and graphical conditions of
equilibrium for coplanar force systems.

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3 Truss: Simple planar trusses and analysis for member forces, methods of
joints and methods of sections
4 Distributed forces, center of gravity and moment of inertia: Center of gravity of
lines, plane areas, volumes and bodies, Pappus-Guldinus Theorem, Moment of
Inertia of Areas, polar moment of inertia, radius of gyration, parallel axes theorem,
moment of inertia of bodies
5 Friction: Theory of friction, static and sliding friction, laws of friction, angle and coefficient of friction, inclined plane friction, glider friction, wedges, belt and rope
friction.
6 Strength and elasticity: Stresses: axial, normal, in-plane, tensile, compressive, shear,
flexural, thermal and hoop, complementary shear.
7 Strain: Linear, shear, lateral, Thermal and volumetric, Poisson’s ratio
8 Elasticity: Elastic, homogeneous, isotropic materials; limits of elasticity and
proportionality, yield limit, ultimate strength, plastic state, proof stress, factor of
safety, working stress, load factor, section of composite materials, prismatic and nonprismatic sections
9 Bending Moment and Shear Force: Types of load, beams and supports, bending
moment and shear force diagrams in statistically determinate beams subjected to
10 Stress in Beams: Theory of simple bending, bending stresses and their distribution,
moment of resistance, modules of sections, distribution of shear stress in different
sections.
11 Torsion: Shaft subjected to Torsion, shear stress, shear strain, angle of twist, power
transmitted by shaft.
Term work:
Atleast 8 experiments based on above syllabus and solution of at least 20 problems.
Text Books:
1. Applied Mechanics by S.B.Junarkar
2. Engineering Mechanics by A.K.Tayal
3. Mechanics of structures Vol-I by S.B.Junarkar & H.J.Shah
4. Strength of Materials by Ramamurth

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1 Introduction to C
Data representation, Flow Charts, Algorithms
Overview of C
Constants, variables and Data types
Operators and Expressions
Managing Input & Output Operators
Decision Making and looping
Arrays
Handling of Character strings
User defined functions
Structures and Unions
Pointers
File Management in C
Dynamic Memory Allocation and Linked List
The Preprocessors
2 Introduction to C++
- Object Oriented Concepts:
Object oriented Development, Objects and classes, generalization and
Inheritance, aggregation
- Object Oriented Programming style and languages:
Object oriented style, reusability, extensibility, class definitions, creating
objects, calling operations, using inheritance, implementing associations,
object-oriented language features.
- Object oriented Languages : an example
Basic programming output using cout, preprocessor directives, variables,
input and output, Manipulators, type conversion, operators, library functions.
- Structures, enumerated data types, simple functions, passing arguments,
overloaded functions, inline functions, default arguments
- A simple class, objects as physical objects and as data types, constructors,
constructor objects as function arguments, returning objects from functions, structures
and classes, classes, objects and memory, static class data, array fundamentals, arrays
as class member data, array of objects, strings.

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binary operators, data conversions
- Inheritance, class hierarchies, public and private inheritance, levels of
inheritance, multiple inheritance, containership, classes within classes, pointers,
memory management, new and delete, pointers to objects, pointers to pointers,
debugging pointers.
- Virtual function, friend functions, static functions, assignment and copy
initialization, this pointer, multiple objects, file pointers, disk I/O, object I/O, I/O
with multiple objects, file pointers, disk I/O with member functions, error
extraction and insertion operations, multi-file-programs, using the project feature.
Textbooks:
1 Programming in C by E.Balagurusami (TMH-95)
2 Programming with C++ by E.Balagurusami(TMH-95)
3 Programming with C by Kernighan and Richie
4 Object Oriented Programming in Turbo C++ by Robert Lafore(Galgotia-1994)
105 – BIOCHEMISTRY
General principles. Buffers. Electroanalytical methods - Potentiometric and
conductometric. Photometry Chromatographic methods of separation - gel permeation,
ion exchange, reverse-phase and affinity chromatography HPLC and FPLC.
Centrifugation. Radiotracer techniques Gel electrophoresis techniques - molecular weight
determination, electroblotting and electroelution, capillary electrophoresis APIelectrospray and MADI-TOF Mass spectrometery. Analysis of carbohydrates, lipids,
proteins and nucleic acids. Enzyme and cell immobilization techniques. Immunochemical
methods of analysis. Biosensors and diagnostics.
Text/references :
1.
2.
3.
4.

D. Holme & H. Peck; Analytical Biochemistry. Longman, 1983.
T.G. Cooper; The Tools of Biochemistry. Wiley Intersciences, 1977.
R. Scopes; Protein Purification - Principles & Practices. Springer Verlag, 1982.

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106 - ENGINEERING GRAPHICS
Part I
1

2
3
4
5

Plane Geometry And Machine Parts
Introduction To Engineering Graphics : Principles Of Projection Lines And
Dimensioning. B.I.S. Code Of Practice (Sp 46) Scale, Representative Fraction,
Plane Scale, Diagonal Scale, Vernier Scale And Scale Of Chords.
Engineering Curves
Classification Of Engineering Curves. Construction Of Conics, Cycloidal Curves,
Involute And Spiral.
Loci Of Points
Simple Mechanism Like Slider Crank Mechanism Four Bar Chain Mechanism
Etc.
Fastening And Connecting Methods
Screw Threads, Bolts, Nut, Stud, Locking Devices, Simple Riveted And Welded
Joints, Pipe Fitting, Couplings, Cotter Joints, Pin Joints.
Electrical Electronics, Chemical And Pipe Drawing, Basic Notation And Symbols For
Simple Flow Diagram.

Part 2 Solid Geometry

6

7
8

Introduction To Projection Of Point, Line And Plane :
Projection Of Line Inclined To Both Planes And Simple Cases, True Length Of
Straight Line And Its Inclination With Reference Planes (Traces Are Not Included),
Projections Of Perpendicular And Oblique Planes.
Introduction To Projection Of Solids, Section Of Solids And Interpenetration Of
Solids
Classification Of Solids, Projection Of Right And Regular Solids With Their Axis
Inclined To Both Planes, Projection Of Sphere, Section Of Pyramid, Cone, Prism
And Cylinder, Method Of Determining Line Of Interesection And Curve Of
Intersection.
Intersection Of Prism-Prism, Cone-Cylinder, Cylinder-Cylinder, Cylinder-Cone,
Cylinder-Prism.
Development Of Surfaces
Parallel Line Development, Radial Line Development, Development Of Sphere By
Zone Method And Lune Method.

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Part 3 Orthographic Projections
Orthographic Projection :
Conversion Of Pictorial Views Into Orthographic Views, Type Of Sections (Full,
Half, Offset, Broken, Removed, Revolved) Section Views, Orthographic Reading,
Missing Views And Missing Line Problems.
9 Isometric View
Conversion Of Orthographic Views Into Isometric Views.
10 Introduction To Computer Aided Drafting
Devices, Types Of Software, Basic Functions, Drafting Softwares.
Part 4 Civil Engineering Drawing
Introduction Of Civil Engineering Drawing.
Plan Elevation, Section And Foundation Plan Of A Residential, Public Bldg.,
Industrial Buildings.
Typical Layout Of Residential, Public And Industrial Buildings.
Drawing Of Building Details Such As
Roofs & Roof Trusses
Column Footings
Simple Machine Foundations
Typical Wall Sections (For 20 Cm, 30 Cm,
40 Cm Thick
Wall)Through Door, Window, Steps, Etc.
RCC Lintel With Chhajjas
Floors
Abbreviation And Symbols Of Building Items, Water Supply And Sanitary,
Electrification, Etc.
Electric Wiring Diagrams For Residential Public And Industrial Buildings And
Domastic Appliances, Standard Electrical Symbols, Main And Distributory Boards,
Simple Earthig Etc.

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
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Term Work :
Part 1,2 And 3
Each Candidate Shall Submit A Set Of The Following Sheets Certified By The
Principal Of The College That They Have Been Executed In A Satisfactory Manner In
The Drawing Halls Of The College.
1 One Sheet Of Engineering Curves.
2 One Sheet Of Loci Of Points.
3 One Sheet Of Projections Of Points, Line And Plane Surfaces.
4 One Sheet Of Orthographic View With Section (Two Problems One In 1st Angle
And Other In 3rd Angle System Of Projections).
5 One Sheet Of Reading Of Orthographic Views And Missing Lines/Missing Views.
6 One Sheet On Projections Of Solids And Sections Of Solids.
7 One Sheet On Development Of Surfaces And Interpenetration Of Surfaces.
8 One Sheet On Isometric Projections/Views.
9 Sketch Book Containing Sketches Of Machine Parts, Electrical, Electronics,
Chemical And Pipe Drawing, Lines, Dimensioning, Scale, Students Are Given
Complete Understanding Of Bis Code Sp 46.
Part 4
1
2

One Sheet On Residential Building Showing Electric Wiring Diagram And
Domestic Applications Standard Electric Symbols, Main And Distribution Boards
And Simple Earthing.
One Sheet On Industrial Structure Layout.

Reference Books :
1
2
3
4
5

Engineering Drawing Vol. I & II P. J. Shah
Engineering Drawing N. D. Bhatt
Civil Engineering Drawing Gurucharansingh
Civil Engineering Drawing Malik And Meo
Machine Drawing N.D. Bhatt

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107 - ELEMENTS OF MECHANICAL AND CIVIL ENGG.
Mechanical Engineering
1. Introduction : Force and Mass, Pressure, Work, Power, Energy, Heat,
Temperature, Units of Heat, Specific Heat capacity, Inter change of heat, Change
of state, Mechanical equivalent of heat, Internal energy, Enthalpy, Efficiency,
Types of prime movers, Sources of Energy.
2 Fuel and combustion: Introduction, Classifications, Solid fuel, Liquid fuel, Gases
fuel, Combustion, calorific values.
3 Properties of gases: Gas law’s: Boil’s law, Charles law, Combined gas law, Gas
constant, Non-flow process, Constant volume process, constant pressure process,
Internal energy, Relations between Cp. & CV, Enthalpy, Isothermal process, Poly
4 Properties of steam: Introduction, Steam formation, Enthalpy, Specific volume of
steam, Steam tables, Internal energy, Non-flow process, Throttling calorimeter,
Separating calorimeter and Combined calorimeter.
5 Heat engine: Thermal prime movers, Elementary of heat engine sources of heat,
Working substances, Converting machines, Sink of heat, Classification of heat
engine, Heat engine cycles, Carnot cycle, Carnot cycle with vapour, Rankine
cycle, Otto cycle, Diesel cycle.
6 Steam Boilers: Introduction, Classification, Simple vertical boiler, Vertical multi
tuber boiler, Cochran type, Lancashire boiler, Locomotive boiler, Marine
Boiler(Scotch type), Babcock and Wilcock boiler, High Pressure boiler, Boiler:Details, Performances, Functions of different Mounting and accessories.
7 Internal combustion Engine: Introduction, Classification, Engine details, Otto four
stroke cycle, Two stroke cycle, Different between two and four stroke cycle,
Indicated Power Efficiency.
8 Speed Control: Introduction, Governors, Steam engine governing, I.C. engine
governing, Flywheel
9 Pump: Introduction, Reciprocating pump-Types & Operations, Bucket Pump, Air
chamber, Centrifugal pump and type of centrifugal pump, Priming, Rotary pump.
10 Air compressor: Introduction, Reciprocating compressor, Operation of
Compressor, Work for compression, Power Required, Reciprocating compressor
efficiency, Multi stage reciprocating compressor, Rotary compressor.
11 Refrigeration and Air Conditioning: Introduction, Refrigerant, Types of
refrigerators, Vapor compression refrigerators, Window air conditioners.
12 Transmission of motion and Power: Introduction, Methods of drive, Power
transmission Elements, Shafting, Belt, Drive, belting, pulleys, Velocity ratio of
pulleys, Power transmitted by a belt, Change drive, Friction drive, Gear drive, Spur
gear, Helical gear, Spiral gear, Bevel gear, Worm gear, Rack and Pinion, Velocity

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ratio of toothed gear, train of wheels, Power transmission by earing, Bearing
classification, Bush bearing, Ball and roller bearings.
Term Work: Based on above syllabus at least five practical
Text books:
1 Elements of mechanical engineering by Hajra Chaudhary
2 Elements of mechanical engineering by Mathur & Mehta
Civil Engineering
1
2

3
4

Surveying: Introduction: Surveying and Leveling, Principle of Surveying, Common
surveying Instruments: Chain, Tapes, Compass, Theodolite, Measurements involved
in surveying and leveling.
Building Construction: Different types of building planning, types of load on
structures, Load bearing and frame structures and Building components,
requirements for different building i.e. Residential, Commercial, Industrial and
Public Building, Masonry construction: Construction of walls, various types of
bonds, Concrete constructions: Common concrete elements like slabs, beams,
column, foundation, lintel etc.
Environmental engineering: Introduction to global environmental problems,
Ecology and Biosphere, Green House effect, Depletion of Ozone and Acid effect.
Transportation Engineering: Introduction, Roads-Types and Material of Construction.
Railways-Types and methods of construction, Classification of Indian Railways, Role
in Transportation
Term Work:Minimum five basic assignments to be carried out.
Text Books:
1 Elements of Civil Engineering by M.B.Gohil & J.N.Patel
Reference Books:
1
2
3

Building construction by B.C.Punmia
Surveying and leveling by T.P.Kanetkar
Environment Engineering by B.S.Kapoor

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Tel: (079)29289540 ; Fax : (079)23243708
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109 - WORKSHOP PRACTICES
Instruction / Demonstration
Should Be Given For Each Of Following Shops / Trade Which Include Importance
Of The Shop / Trade In Engineering, New Materials Available, Tools / Equipments
Required Indicating The Use Of Each Tool / Equipment, Methods Of Processing
Any Special Machines, Power Required Etc.
1. Joining Process
2. Sheet Metal Work
3. Plumbing (Metalic & Non Metalic Pipe Fittings)
4. Electro Plating
6. Manufacture Of Plastic Products
7. Metal Machining , Turning, Drilling, Grinding Etc.
8. Carpentry / Pattern Making
9. Fitting / Assembly Practice
10. Forging And Hot Working Processes
11. Moulding And Casting Processes
Exercise And Term Work:
Each Student Is Required To Prepare Simple Exercises In Following So As To
Have A Feeling Of How The Jobs / Parts Are Prepared And Use Of Tools /
Equipments (Any Eight)
1
2
3

Electroplating - 1 No
Painting Of Metal Piece - 1 No
Sheet Metal Part - 1 No
4. Plumbing - 1 No
5 Arc Welding / Gas Welding / Welding - 1 No
6 Soldering / Brazing - 1 No
7 Drilling Practice - 1 No
8 Fitting / Assembly - 1 No
9 Carpentry Practice - 1 No
10 Forging Practice - 1 No
Over And Above These Exercises Each Student Is Required To Prepare A Laboratory
Report On Instruction / Demonstration And Exercises Prepared By Him As A Part Of His
Termwork.

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B.E SEM III
301 - MATHEMATICS-III
1. Fourier series: Periodic functions, Drichlet's conditions, Fourier series, Euler's
formula. Fourier expansion of periodic functions with periodic functions with
period 2π, Fourier series of even and odd functions. Fourier series of periodic
functions with arbitrary periods, half range Fourier series. Harmonic analysis.
2. Laplace Transform: Motivation, definition, Linearity property, Laplace
transforms of elementary functions, shifting theorem. Inverse Laplace
transforms, Laplace transforms of derivatives and integrals, Convolution
theorem, Application of Laplace theorems in solving ordinary differential
equations, laplace transforms of periodic, Unit, step and impulse functions.
3. Ordinary differential Equations: Linearity differential equations of higher
order with constant coefficients, Method of variation of parameters, Higher
order linear differential equations with variable coefficients (Cauchy's and
legendre forms), Simultaneous linear differential equations, Models for the
real world problems and their solutions in particular, Modeling of electric
circuits, Deflection of beams, Free oscillations, forced oscillations,
Resonance, Solution of Bessel and Legendre equations by series method,
Definition and properties of Bessel's functions, Legendre functions by series
method, Definition and properties of Bessel's functions, Legendre's
polynomials and properties like recurrence relations, orthogonality.
4. Partial Differential equations: formation of differential equations, Directly
integrable equations, Models of engineering problems leading to first order
partial differential equations, Lagrange's equation, Solutions of special type of
first order partial differential equations, homogeneous linear equations with
constant coefficients, application of partial differential equations, Boundary
value problems and method of separation of variables, Modeling of vibration
of a stretched string - one dimensional wave equation.
5. Numerical methods: Motivation, Errors, Truncation error, Rounded off error,
Absolute error, Relative error and percentage error, solution of algebraic and
transcendental equations by Newton-Raphson method, Bisection, False
position and iteration and extended iteration methods, Convergence of these
methods.
Reference Books:
1. Higher Engineering mathematics, by Dr.B.S.Grewal, Khanna publishers,
New Delhi.

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2. Engineering Mathematics vol- II, by Prof. Wartikar & Wartikar Pune
Vidhyarthi Gruh, Pune.
3. Engineering Mathematics by Dhavan & Shrivastava, Dhanpatrai & Sons,
New Delhi.
4. Engineering Mathematics- Vol I & II, by S.S.Sastry, prentice Hall of India,
New Delhi.
5. Mathematics for engineering students, by P.D.S Verma kalyani publishers,
Ludhiyana and Delhi.
6. A textbook on engineering by N.P.Bali, Ashok Saxena & Iyengar, Laxmi
publications (p) ltd. New Delhi.
7. Engineering mathematics vol-I, II & III by Kandaswamy, Thilagvati &
Gunavathi, S.Chand & Co. (p) ltd, New Delhi.
8. A first course in mathematics for Engineering, Mathematics for engineers,
9. Engineering mathematics vol I, II, III&IV by Kumbhojkar,
10. Engineering Mathematics- Vol I by Chintamani das, New central book
agency (P) ltd, Calcutta.
11. Advanced Engineering Mathematics (Fifth Edition), by Erwin Kreyszig,
Willey Eastern Ltd., New Delhi.
302 - CIRCUIT THEORY
1. Circuit Concept: Charge and Energy, The relationship of field and circuit
concepts, Capacitace, Resistance and Inductance parameter Units and Scaling,
Approximation of a physical system as a circuit..
2. Network Cinvention: Referance direction for current and voltage, Active element
convention, Dot convention, Topological Description.
3. Network Equations: Kirchoff’s law, The no of network equations, source
transformation, loop variable analysis, Node variable analysis, Determinants,
Minors, and Gauss Methods, Duality, State variable analysis.
4. Initial conditions in network: Initial condition in elements, Geometrical
Interpretation of Derivatives, Procedure for Evaluating initial conditions, Initial
state of network.
5. Solution of differential equation by classical and Transform methods: Second
order equation, Higher order equation, Network excited by external energy
sources ,response as related to s-plane location of the roots.

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6. Transform of other signal waveforms: Unit step function, Ramp and impulse
function, waveform synthesis, initial value and final value theorems.
7. Impedance Functions and network theorems: concept of complex frequency,
Transform impedance and transform circuits, series and parallel combinations of
elements, superposition and reciprocity, Thevenin and Norton theorem.
8. Network Functions: Poles and Zeros: Terminal pairs, network functions for the
one port and two port, calculation of network function, poles and zeroes of
network function, Restrictions on poles and zero locations for driving point
function, Time domain behavior from the pole and zero plot, Stability of Activity
Networks.
9. Two port parameters: Relationship of Two port variables, Short Circuit
Admittance parameter, The open circuit impedance parameter, Transmission
parameters, The Hybrid parameters, Relationships between parameter sets,
parallel connection of two-port networks
10. Sinusoidal steady state analysis: The sinusoidal steady state, The sinusoid and
ejwt, solution using ejwt , solution using real and imaginary part, phasor and
phasor diagram.
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. Network Analysis (3rd Edition)-by Van Valkenburg
2. Network Analysis-by G.K.Mithal

303 - Human Anatomy.and Physiology
1. Cell and Tissues:
Physical Structure of the Cell; Functional System of the cell-Transport of Ions and
Molecules through the cell membrane; Membrane Potentials and Action Potentials;
Inhibition of Excitability; Recording Membrane potentials and Action potentials.
2. Respiratory System:
Structure of Respiratory tract, Lungs, Diaphragm. Mechanics of Pulmonary
Ventilation, Pulmonary Volumes and Capacities. Physical Principle of Gas Exchange.
Pulmonary function testing. Artificial Respiration.

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3. Cardiovascular System:
Structure of Heart, Heart valves, Arteries, Veins, Coronary Circulation.
Heart as a pump, Physiology of Cardiac muscle, Cardiac Cycle. Rythmic excitation of
heart. Control of excitation and conduction in the heart. Introduction of ECG and
cardiac activity. Physics of Blood pressure, flow and resistance. Vascular
distensibility and functions of Arterial and Venous Systems. Heart rate and normal
Heart sounds.
4. Body Fluid:
Blood and its composition and function. Various Cells and their structures. Numbers Cell
counting, Haemoglobin and its estimation, Anaemia, Blood counts and ESR.
5. Skeletal and Muscular System:
Structure and Formation of bone; Types of bones, joints, Classification of movements;
Classification of muscles- Muscle contraction mechanism, EMG.
6. Nervous System:
Outline of Cranial and Spinal nerves. Structure of Spinal Cord and different Brain parts.
Vertibral column and Cranial cavity. Excitation of skeletal muscle- Neuro muscular
transmission, Excitation-Contraction Coupling, Contraction of Smooth muscle. General
design of Nervous System- CNS- its function, Synapes, Receptors, Types of Sensation.
EEG.
7. Excretory System:
Structure of Kidney, Formation of Urine, Concentration and Dilution of Urine, Renal
Function Tests, Artificial Kidneys, Dialysis.
8. Special Senses:
Vision: Eye as a camera, Mechanism of accomodation, Visual accuity, Ophthalmoscope,
Colour vision, Perimetry.
Hearing: Tympanic membrane and the Ossicular system, the cochlea, Hearing mechanics
and abnormality, Deafness, Audiometry.
9. Reproductive System:
Spermatogenesis; Semen; Ovarian cycle physiology.
10. Endocrine System:
Physiological actions of the hormones secreted by: Pituitary, Thyroid, Parathyroid, Islets
of Langerhans, Adrenal, Testes and Ovaries. Bio feedback

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mechanism of hormone regulation. Homeostasis- Regulation of Internal
Environment.
11. Functions of the Skin.
Term Work and Practicals shall be based on the above syllabus.
Books:
1. Anatomy and Physiology in Health and Illness.
Ross and Wilson .
By- Anne Waugh. Allison Grant.
2. Illustrated Physiology.
By- Mc Naught, Callander.
3. Human Anatomy: Regional and Applied.
By- Chaurasia, B.D.
4. Physiology of Human Body.
By- Guyton.
5. Engineering Principles of Physiological Functions.
By- Chneck.
6. Grants Atlas of Anatomy.
By-Agar.
7. Principled of General Anatomy.
By- A.K.Datta.
8. Human Anatomy and Physiology,1995.
By- Van Wynsherge.D, Noback, C.R and Caroia R.
304 - BASIC ELECTRONICS
1. Introduction to electronics theory: atomic structure, terminologies, bohr’s
postulate, electron theory, energy band diagram, ionization potential, metal,
semiconductor, insulators.
2. Semiconductor theory: transport phenomenon in semiconductors-mobility,
conductivity, drift, diffusion, concept of hole, semiconductor materials, types of
semiconductors, mass action law, hall effect, generation and recombination of
charges, continuity equation, potential variation in graded semiconductor.
3. Semiconductor diodes: introduction, ideal diode, resistance levels, equivalent
circuits, switching characteristics, notation of diode and its testing, zener diode,
LEDs, diode arrays,
4. Diode applications : Load line analysis, diode approximations, series diode
config. With DC inputs, parallel and series – parallel config.AND / OR gates,

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sinusoidal inputs, half wave and full wave rectifications, clipper, clampers, zener
diode, voltage multipliers.
5. Special purpose devices: schottky barrier diodes, varactor diodes, power diodes,
tunnel diodes, photodiodes, photoconductive cells, IR emitters, LCD, solar cells,
thermistors.
6. Bipolar junction transistor: construction, operation, various configurations, limits
of operation, notation, specifications and their use, testing, casing and terminal
identification.
7. DC biasing of BJTs: operating point, fixed bias ckt., emitter stabilized ckt.,
voltage divider bias, dc bias with voltage feedback, miscellaneous bias
configurations, design operations, switching networks, bias stabilization.
8. BJT transistor modeling: amplification in the AC domain, transistor modeling,
important parameters: Zi, Zo, Av, Ai, The re transistor model, hybrid equivalent
model, graphical determination of h-parameters, variation of transistor
parameters.
9. Field Effect Transistors: construction and char. of JFET, transfer char, important
relationship, depletion type MOSFET, enhancement type MOSFET, MOSFET
handling, VMOS, CMOS.
10. FET biasing: fixed bias, self bias, voltage divider bias, depletion type MOSFET,
enhancement type MOSFET ,combination networks, design, trouble shooting,
universal JFET bias curve.
11. Discrete and IC manufacturing techniques: introduction, semiconductor materials,
discrete diodes, transistor fabrication, integrated circuits, monolithic integrated
ckt., production cycle, thin film and thick film integrated circuits, hybrid
integrated ckts.
The Practical and Term work will be based on the topics covered in the syllabus.
Text book:
1. Millman - Halkias, “ Integrated Electronics – Analog and Digital circuits and Systems
“, Tata MacGraw- Hill.
2. Robert Boylestad “Electronic devices and circuit theory” ,PHI edition.

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305 - DIGITAL TECHNIQUES
1. Introduction To Digital Circuits:
Binary systems, number base conversion, octal and hexa-decimal numbers,
Complements, Binary codes, binary storage and registers, binary logic, Boolean
algebra and logic gates, basic theorems and properties of Boolean algebra,
Boolean functions, canonical and standard forms of Boolean functions, digital
logic gates, simplification of Boolean functions, map method,

2.

3.

4.
5.

6.
7.
8.
9.

Two to six variable maps, NAND-NOR implementation and other two level
implementation, don’t care conditions, tabulation method, determination and
selection of prime implicants.
Combinational Logic Circuits:
Adders, subtractors, Code converters, Analysis procedure, multilevel NAND –
NOR ckts. EX-OR and equivalence functions . Binary and decimal parallel adder
, magnitude comparator , Decoder, multiplexer, ROM and PLA .
Sequential Logic Circuits:
Flip-flops, triggering of Flip-flops, anal conversion of flip-flops, Analysis of
clocked sequential ckt. State reduction and assignments Flip-flop excitation
tables. Design procedure , design of counters, design with state equations.
Registers, counters And Memory Unit :
Registers, shift registers, ripple counters, synchronous counters, timing sequences,
memory unit.
Register transfer logic
Inter register transfer, arithmetic logic and Shift micro operation, conditional
control statements, fixed point binary data , over flow, arithmetic shifts, decimal
,floating points, non numeric data, Instruction codes.
Processor Logic Design
Processor organization, Arithmetic logic unit (ALU)Design of arithmetic, logic
and arithmetic-logic ckts. Status registers, Processor unit, Design of accumulator.
Control Logic Design
Control organization Micro program control, Control of processor unit
PLA control, micro program sequencer.
Computer Design
System of configuration, Computer instructions, Timing and control
Execution of instruction, Design of computer registers & control.
Digital Integrated Circuits.Digital IC specification terminology
Logic families- RTL, DTL, TTL, I2L, ECL, MOS, CMOS, Interfacing

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The Practical and Term work will be based on the topics covered in the syllabus.
BOOKS :
Morris Mano, “Digital logic and computer design”, PHI.
A Anand kumar, “Fundamentals of digital circuits “, PHI
306 - Instrumentation Workshop
Instruction / Demonstration Should Be Given For Each Of Following:
1. Tools and their use: pliers, cutter, stripper, screw driver, crimping tool, soldering
iron etc.
2. Understanding of single phase and three phase wiring.
3. Understanding of switch accessories, wires and cables.
4. Understanding and use of multi-meter, tester, series lamp, megger.
5. Understanding of house wiring, fuse, earthing, MCB, ELCB.
Exercise on:
1. Fan wiring
2. Tube light wiring.
3. Staircase wiring
4. Application of series lamp for troubleshooting of electrical appliances.
5. Soldering practice.

Over And Above These Exercises Each Student Is Required To Prepare A Laboratory
Report On Instruction / Demonstration And Exercises Prepared By Him As A Part Of His
Term work.

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B.E. SEM IV
401 - Applied Mathematics
1. Vector Calculus: Reorientation, Differentiation of vectors, Scalars and vector
fields, Gradient of a scalar function, Directional derivative, Divergence and curl
of a vector function and their physical meanings, Line Surface and volume
integrals, Green's theorem, Gauss and stoke's theorems (Without proof),
Irrotational, Solenoidal and conservative vector fields. Curvilinear coordinates
(Cylindrical and spherical polar), applications.
2. Functions of complex variables: Reorientation, Analytic function, CauchyRiemann equations (Cartesian and polar forms), Harmonic functions, conformal
mappings, Complex integration, Cauchy's theorem and integral formula,
Singularities, Taylor's and Laurent's series, Residue theorem, Evaluation of
integrals using residues.
3. Fourier Transforms: Fourier integral theorem (only statement), Fourier sine and
cosine integrals, Complex form of Fourier integral, Fourier sine and cosine
transforms, Inverse laplace transforms by residue, Solutions of boundary value
problems using Fourier transforms. Application to transverse vibration of a string
and transmission lines.
4. Solution of cubic by Cardon and biquadratic equations by Ferrari's method.
5. Matrices: Cayley- Hamilton Theorem, Special matrices like hermitian, SkewHermitian and unitary, Quadratic forms.
Reference Books:
1. Higher Engineering mathematics, by D.B.S.Grewal, Khanna Publishers, New
Delhi.
2. A textbook on Engineering mathematics, N.P.Bali, Ashok Saxena & Iyengar,
Laxmi publications (p) ltd, New Delhi.
3. Engineering mathematics- Vol -III by Prof. Wartikar & Wartikar, Pune
Vidhyarthi Gruh, Pune.
4. Mathematics for engineers, advanced mathematics for engineers, by
5. Advanced Engineering Mathematics by Erwin Kreyszig, (Fifth Edition), wiley
Eastern Ltd., New Delhi.

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1. Operational amplifiers: introduction, differential and common mode operation,
op-amp basics, practical op-amp circuits, op-amp parameters.
2. Op-amp applications: constant gain multiplier, voltage summing, voltage buffer,
controlled sources, comparators, instrumentation circuits, integrator,
differentiator, log and anti log amplifier, full wave, half wave rectifier, active
filters.
3. Feedback and oscillator circuits: feedback concepts, feedback connection types,
practical feedback circuits, feedback amplifier- phase and frequency
considerations, oscillator operation, phase shift oscillator, Wien bridge oscillator,
tuned oscillator, and crystal oscillator.
4. Linear Wave-shaping circuits: introduction, RC high pass and low pass circuits,
response to standard input signals.
5. 555 Timer: introduction, operation, 555 as astable, bistable, monostable
multivibrator, applications.
6. BJT small signal analysis: common emitter fixed bias, voltage divider bias,
emitter bias and emitter follower configurations, common base configuration and
collector feedback configuration, collector DC feedback configuration.
Approximate hybrid equivalent model
7. Systems approach- Effects of Rs and RL: Two port systems, effect of load
impedance and source impedance, combined effect of R s and RL, BJT CE, CB,
Emitter follower networks, FET networks, cascaded systems.
8. BJT and JFET frequency response: introduction, logarithms, decibels, general
frequency considerations, low frequency analysis- bode plot, low frequency
response for BJT and FET amplifier, miller effect capacitance, high frequency
response of BJT and FET amplifier, multistage frequency effects, square wave
testing
The Practical and Term work will be based on the topics covered in the syllabus.
Text book:
1. Robert Boylestad- “ Electronic devices and circuit theory “- PHI edition.
2. Millman - Halkias, “ Integrated Electronics – Analog and Digital circuits and Systems
“, Tata MacGraw- Hill

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403 - BIOMEDICAL TRANSDUCERS

1. Generalised Instrumentation Scheme:
Transducers and their Static and Dynamic performance characteristics. Electrical
Design Consideration.
2. Transduction Principles:
Resistive, Inductive and Capacitive Transduction; Photoconductive and Photo
voltaic Transduction. Fibre Optic Sensor. Strain Gauge- types, construction,
selection materials, Gauge factor, Bridge circuit, Temperature compensation.
LVDT- construction, sensitivity, merits etc. Capacitive Transducer- variable
seperation, variable area and variable dielectric type; merits and demerits.
Piezoelectric Transducer: piezo crystals- output equation, mode of operation,
merits and demerits.
3. Temperature Transducers:
Thermo resistive transducer- RTD and Thermister; Thermo emf Transducerthermo couples; Non contact type infrared thermometry; optical pyrometer.
Thermister used for cardiac output measurement, nasal air flow measurement.
4. Pressure Transducers:
Extra vascular and Intra vascular pressure sensors; Strain Gauge type Blood
pressure transducers; Diaphragm type capacitive pressure transducer; Piezo
electric pressure transducer; Intra vascular fibre optic pressure transducer; Fibre
optic pressure transducer for intracranial pressure measurement in new borns;
Tonometry; Stethoscopes; Phonocardiograph sensor.
5. Flow Transducers:
Electromagnetic Blood flow transducer; Elasto resistive plethysmographic
transducer; Air flow transducer for Fleish pneumotachometer; Ultrasonic flow
transducer.
6. Displacement Transducers:
LVDT and resistive potentiometric transducers for translational and angular
displacement measurement; Strain gauge displacement transducer; capacitive and
displacement transducer for respiration sensing.

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Ionization transducer- GM counter; Scintillation transducer- Scintillation counter.
8. Bioanalytical Sensors:
Enzyme based glucose sensor; Microbial biosensor for ammonia and nitrogen
dioxide; optical biosensor for antibody-antigen detection. Blood-gas sensorsPolarographic clark PO2 sensor; Transcutaneous PO2 sensor, PCO2 electrode,
SO2 sensor of pulse oximeter.
9. Biopotential Measurement:
Electrode-Electrolyte interface, half cell potential, Polarization- polarizable and
non-polarizable electrodes, Ag/AgCl electrodes, Electrode circuit model;
Electrode and Skin interface and motion artifact.
Body Surface recording electrodes for ECG, EMG, EEG and EOG. Electrodes
standards. Internal Electrodes- needle and wire electrodes. Micro electrodesmetal microelectrodes, micropippet electrodes. Electrical properties of micro
electrodes. Electrodes for electric simulation of tissue; Methods of use of
electrodes.
Term Work and Practicals shall be based on the above syllabus.
Books:
1. Biomedical Sensors- Fundamentals and applications.
By- Harry.N. Norton.
2. Transducers for Biomedical measurements. ( Principles and Applications.)
By- Richard S.C. Cobbold.
3.Medical Instrumentation application and design.
By- John G. Webster.
4.Principles of Applied Biomedical Instrumentation.
By- Geddes,L.A and Baker,L.E
5. Bio-Sensors. By-Hall, E.A.H.
6. Biomedical Transducers and Instruments (CRC Press)
By- Tatsoo Togawa., Toshiyo Tamura, P. Ake Ober

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404 - CONTROL THEORY
1.

2.

3.
4.
5.

6.

Introduction to Control system :
Introduction, Examples of Control Systems, Closed-Loop Control Versus OpenLoop Control, Design Of Control Systems.
Mathematical Modeling :
Introduction, Transfer Function and Impulse-Response Function, Block Diagrams,
Modeling in State-Space, Mechanical Systems, Electrical Systems, Liquid – level
Systems, Thermal Systems.
Transient Response :
Introduction, First-Order Systems, Second-Order Systems, Transient-Response
Analysis with MATALAB, An Example Problem Solved with MATALAB.
Basic Control Systems
Introduction, Higher-Order Systems, Routh’s Stability Criterion, Steady-State
Errors in Unity –Feedback Control Systems.
Root Locus:
Introduction, Root-Locus Plots, Summary of General Rules For Constructing
Root Loci, Root-Locus Plots with MATALAB, Special Cases, Root-Locus
Analysis of Control Systems , Root Loci for Systems with Transport Lag, Root
Contour Plots.
Frequency Response :
Introduction, Bode Diagrams, Plotting Bode Diagrams with MATALAB, Polar
Plots, Drawing Nyquist Plots with MATALAB, Log-Magnitude Versus Phase
Plots, Nyquist Stability Criterion, Stability Analysis, Relative Stability, Closed
Loop Frequency Response, Experimental Determination of Transfer Functions

The Practical and Term work will be based on the topics covered in the syllabus.
Text Books :
K.Ogata , “Modern Control Engg.” , Prentice Hall of India Pvt. Ltd. , 3rd edition.
References :
Nagrath Gopal, “ Control system Engineering “, Wiley Eastern

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405 - ELECTRICAL AND ELECTRONIC MEASUREMENT
1. Experimental Data & Errors: Measurement Recording and Reporting, Graphical
presentation of data, Precision & Accuracy, Resolution & sensitivity, Errors in
Measurement, Statistical evaluation of measurement data and errors, The decibel,
Problems
2. Analog DC and AC meters: Electromechanical meter movements, Analog DC
ammeters, Analog DC voltmeters, Analog AC ammeters and voltmeters, Analog
multimeters, Special purpose analog meters, How to use basic meters, Meter
errors, problems.
3. Oscilloscope: Oscilloscope subsystem, Display sub system, Vertical deflection
subsystem, Dual trace Feature, Horizontal Deflection subsystems, oscilloscope
probes, oscilloscope controls, How to operate an oscilloscope, oscilloscope
photography, Special purpose oscilloscope, Problems.
4. Time & Frequency Measurement: Time measurements, Frequency measurements,
Harmonic Analysis and spectrum analyzers, Problems.
5. Power & Energy Measurement: Power in Ac circuits, single-phase power
measurements, Polyphase power and measurement, Electrical energy
measurements, power measurements at high frequency, problems.
6. Resistance and measurement of Resistance: Resistance and resistor, resistor type,
color coding of resistor, measurement of resistance, wheaston Bridges, Making
balanced wheaston bridge measurement, Low value resistance measurement,
Problems.
7. Measurement of Capacitance, Inductance, and Impedance: Capacitance and
capacitors, capacitor circuit models and losses, capacitor types, color coding of
capacitors, Inductor and inductance, Inductor structure, Transformers, Impedance,
Capacitance and Inductance Measurement, complete impedance measurement,
Problems.
8. A.C.signal source: Oscillators, sweep frequency Generators, Pulse generators,
function generators.
9. Interference signals and their elimination: capacitive interference, inductive
interference and shielding, electromagnetic interference and shielding,
conductively coupled interference, ground loop interference and input guarding to
reduce it, internal noise.
The Practical and Term work will be based on the topics covered in the syllabus.

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Text book:
1. Wolf & Smith, “Student Refrence Manual for Elelctronic and Instrumentation
measurement:”, PHI .
Reference book :
Cooper, “Electronic Instrumentation and Measuring Techniques”, PH
406 - Simulation Packages

Following packages to be studied..
Simulation programs needs to be carried out from the above packages and term
work and practical should be based on the same.

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B.E. SEM V
501 - MICROPROCESSOR, INTERFACING & APPLICATIONS
1. Introduction to Micro Computers, Micro Processors:
Introduction to digital computer, Data representation, microprocessor
organization, memory, input output devices, system bus.
2. Micro Processor Architecture and Micro Computer Systems:
Microprocessor 8085 architecture, operation, memory, and interfacing devices
3. Instructions and Timings:
Data transfer group instruction, branching group, arithmetic instruction, logical
instruction, special purpose instruction, time diagram of single byte, two byte, three
4. Assembly Language Programming:
Programming using data transfer instruction, arithmetic and logical instruction
branching instruction, subroutine and stack, time delay and counter implementation,
code conversion.
5. Interrupts:
Vector interrupts, priority of interrupts, interrupt level
6. Parallel I / O and Interfacing applications.:
Basic interfacing concepts, interfacing displays and memories.
7. Code converters:
Data converters, ADC, DAC,their types & construction ,their interfacing with 8085.
8. Interfacing of Multipurpose programmable devices:
8155/8156,8355/8755,8279 programmable keyboard/display interface
9. Interfacing of General purpose programmable peripheral devices:
8255A PPI, 8253 programmable interval timer, and 8259A programmable
interrupt controller, DMA & 8257 DMA controller
10. Serial I / O and data applications.:
Serial I/O data communication & bus interfacing standards, basic concepts in serial
I/O using programmable chips, bus standards-RS 232,IEEE 488.
11. EPROM and RAM memories. 2764 and 6264
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
 Ramesh Gaonkar
- “Micro Processor Architecture, Programming and
Applications with 8085/8080A “ – Wiley eastern limited.

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P.K. Ghosh and P.R. Shridhar – “0000 to 8085 – Introduction to micro Processors
for Engineers and scientists” – Prentice hall of India Pvt. Ltd
2nd edition
502 - DIAGNOSTIC TECHNIQUES & INSTRUMENTATION
SECTION: A: -

MEDICAL DIAGNOSTIC TECHNIQUES

CARDI1OVACULAR
DISEASES
AND
THEIR
DIAGNOSIS: ECG,
Phonocardiography, Blood pressure & Heart rate measurements, Blood flow
measurements, Doppler.
RESPIRATORY DISORDERS AND THEIR DIAGNOSIS:X -rays, Volumes &
capacity (Spirometry), Bronchoscopy, Laryngioscopy, etc.
G. I. TRACT DISORDERS THEIR DIAGNOSIS: Laparoscopy, Cystoscopy, Upper
G. I. Endoscopy, Colonoscopy, Sigmoidoscopy, Protoscopy.
METABOLIC DISORDERS AND THEIR DIAGNOSIS: Thermometry, Oxygen &
Carbon - dioxide content and pressure, various enzyme assays. Diseases related to
Kidney & Urinary system and their diagnosis.
NERVOUS SYSTEM DISORDERS AND THEIR DIAGNOSIS: EEG, SER,
EMG, Scanning Techniques etc.
OCULAR DISORDERS AND THEIR DIAGNOSIS: Perimetry, Refractometry,
Tonometry, Ophthalmoscopy, Ultrasound, VER, ERG, EOG, ENG etc.
Auditory disorders and diagnosis: AER, Audiometry etc.
 Obstetric & Gynecological problems and their diagnosis like USG & Endoscopy.
 Biotelemetry and their clinical significance.
SECTION: - B

MEDICAL DIAGNOSTIC EQUIPMENTS

ELECTROCARDIOGRAPH:The ECG waveform, Block-diagram, Front panel,
Controls, ECG Pre-amplifier, ECG recorders.

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ELECTROENCEPHALOGRAPH:EEG waveform (Frequency range & Amplitude),
Multi channel recording system & control panel details, Block - diagram, Pre-amplifier &
filter circuits.
INSTRUMENTS
FOR
MEASUREMENT
OF
PHYSIOLOGICAL
PARAMETERS:Electronic manometer, Electro-sphygmomanometer, Electronic
stethoscope, Blood flow meter, Thermometer, Tonometer, Auto- refractrometer, Spiro
meter, Audiometer.
DIAGNOSTIC X-RAY MACHINE: Generation, Fluoroscopy and Image Intensifier,
Fundamentals only.
Diagnostic Ultrasound:Principle of measurements, Ultrasound imaging, Foetal
monitor, Echocardiograph, Echoencephalograph.
The Practical and Term work will be based on the topics covered in the syllabus.
BOOKS :

Diagnosis Procedures in Cardiology - Warren & Lewis
-Atul Lutre
Practical Echocardiography -Setu Raman
Prenatal Diagnosis and Therapy -A. Chakraborthy
Bio-Medical Instrumentals & Measurements -Cromwell
Bio-Medical Instrumentation
-R. S. Khandpur
Medicine and Clinical Engineering -Bertil Jocobson& John Awebster
503 - ANALYTICAL & OPTICAL INSTRUMENTATION
SECTION:A

ANALYTICAL & OPTICAL DIAGNOSTIC TECHNIQUES

1. Principle involved in Biochemical, Pathological & microbiological laboratory
techniques in clinical diagnosis.
2.

Instrumentation techniques:
1. Use of general instruments like Incubators, autoclaves, centrifuges, hot air oven,
Balances, Auto pipettes.
2. Microtome, Processing like automatic tissue processing ("Histokinette”)

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3. Laboratory counters; anaerobic apparatus, Laminar flow tables, Culture
Techniques, Blood
banking procedure & Instruments.
3. Analytical techniques like Spectrophotometry, Colorimetry, Auto analysis, Semi auto
analysis,
gas & electrolyte analysis, flame photometry, chromatography, Chromatography,
Electrophoresis, Glucometry, Measurement of pH, RIA units. PCR units , ELISA
Dispenser & washer, Pulse-oxymetry, Capnography, Arterial blood analysis etc and
their
significance in different diagnosis and prognosis of various clinical disorders.
4. Microscopy - simple, compound, binocular, trinocular, dark ground microscopy
Phase contrast microscopy, electron microscopy, CCTV, microphotography &
projection etc &
their importance in clinical diagnosis.
5. Special microscopy like endoscopy. use of fiber optics.
SECTION:B ANALYTICAL & OPTICAL DIAGNOSTIC EQUIPMENTS
Study of principle of operation, Block-diagram; Circuit diagram, Control panel,
specification, Design aspects & Applications of the following Equipments:
1. Incubators, autoclaves, centrifuges, hot air oven, Balances, Auto pipettes, microtome,
Processing like automatic tissue processing ("Histokinette”), Laboratory counters;
Anaerobic apparatus, Laminar flow tables, Spectrophotometer, Colorimeter, Auto
analyzer, Semi auto analyzer, flame photometer, Glucometer, pH meter, RIA units.
PCR units, ELISA reader, Dispenser & washer, Pulse-oxymeter, Arterial blood
analyzer.
2. Endoscopes.
3. Microscopes of various types including electron microscope.
4. Chromatograph.
5. Electrophoresis apparatus.
6. Blood Gas Analyzers:
Blood PO2 Measurement; Measurement of blood PCO2; Complete Blood Gas
Analyzer.
7. Blood cell counter:
Method of cell counting, coulter counter, automatic recognition and differential
counting of cells.

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The Practical and Term work will be based on the topics covered in the syllabus.
BOOKS:
1. Medical laboratory technology (Methods & Interpretation)- Ramnik sood, 5th
Edition .jaypee
2. Wildman's: Clinical interpretation of laboratory tests- Sacher, 10th edition. Jaypee
3. Interpretation of common investigations- Gupta & Gupta., 4th edition .jaypee
4. The text book of Blood bank and transfusion medicine.- Satish Gupta. 1st edition,
Jaypee
5. Principle clinical Biochemistry - Chavda R,
6. Clinical diagnosis and management by laboratory methods- Henry, 19th
Edition, Anuja book company
7. Bio-medical Instruments & Measurement - Cromwell.
8. Bio-medical Instrumentation- R S. Khandpur
9. Medicine and clinical engineering - Bertil Jacobson & john Webster.
504 - BIOMATERIALS & IMPLANTS
1) Introduction To The Use Of Non-Pharmaceutical Biomaterials:
Types: Synthetics,Metals & Non Metallic Alloys, Ceramics,Inorganics & Glasses .
Bioresorbable & Biologically Derived Materials , Bioderived Macromolecules, Tissue
Medical Device Design Requirements, Material Selection Criteria, Preclinical
Testing.
2) Polymers:
Polymerization, Polyethylene, Prosthodontic Polymers, Clinical Study Of Soft
Polymers, Bloerodible Polymers, Blood Compatible Polymers, Bioactive Polymers,
Hydrogels, Hard Methacrylats, Drug Incorporation Polymer Gels, Biocompatibility
Of Polymers-Blood Compatibility Improvement, Compatibility Evaluation.
3) Metals, Metallic Alloys & Ceramics:
Stainless Steel, Titanium & Titanium Alloys, Cobalt Based Alloys, Nitinol, CeramicsIntroduction To Bio Medical Usages-Bonding Natural Tissue. Bio-Active Glass,
High Density Alumina , Calcium Phosphate Ceramics-Porous Materials,Biological
Interactions, Dental Ceramics-High Strength Materials-Thermal Expansions, Fracture
Toughness. Drug Delivery from Ceramics. Wet Chemical Synthesis.

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4) Composite Bio-Materials:
Soft Composites, Dental Composites, Saline, Coupling Agents, Microfield Materials,
White –Light Systems Bonding To Teeth. Clinical Trials, Synthesis of Fillers, Matrix
Resins, Mechanical & Physical Evaluation.
5) Mechanical Properties:
Standards & Assessments of Bio-Materials, Surface Properties of Biomaterials &
Their Testing.
6)
Bio –Compatibility:
Tissue Reaction to External Materials, Blood/Biomaterial Interaction. Corrosion &
Wear of Bio-Materials. Treatment of Materials for Bio-Compatibility, Biodegradable
Materials & Their Applications, Rheogical Properties of Biological Solids-Bone
Tendons, A Blood Vessels, Biological Liquids, Mucus Etc.
7) Implant Surgical Devices, Rehabilitation Devices Used For Physiological Functions
Of Human Body Systems- Improvement Or Replacement
The Practical and Term work will be based on the topics covered in the syllabus.
Books
1) Bio-Materials-An Interfacial Approach.
- Hence, L.I & Ethridge E.
2) Bio-Materials Science & Engineering.
- J.V. Park
Plenum Press, Newyork
3) Bio-Materials Medical Devices & Tissue Engineering
- Fredrick H. Silver
Chapman & Hall , London
4) Human Bio-Materials Applications.
- Wise
505 - MODERN DIGITAL AND ANALOG COMMUNICATION
1. Introduction
Communication systems, Analog and digital messages, S/N Ratio, Channel
Bandwidth and the rate of communication, Modulation.
2. Introduction to signals
Introduction to signals, Classification of signals, Signal operations, Unit impulse
functions, Correlation.

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3. Analysis and Transmission Of Signals
Signal transmission through a linear system, Signal distortion over a
communication channel, Signal energy and energy spectral density, Signal power
and power spectral density.
4. Linear Amplitude Modulation
Base band and carrier communication, DSB, AM, QAM, SSB, Carrier acquisition,
5. Sampling and Pulse Code Modulation
Sampling theorem, PCM, DPCM
6. Principles of Digital Data Transmission
Digital communication system, Line coding, Pulse shaping, Scrambling,
Detection-Error probability, Digital carrier systems, Digital multiplexing
7. Emerging Digital Communications Technologies
The North American Hierarchy, Digital services, Broad band digital
communication
8. Miscellaneous
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1) "Modern Digital and Analog Communication Systems”,3rd Edition, B.P.Lathi,
Oxford.
2) “Electronic Communications Systems", George Kennedy, TMH.
3) "Electronic communication systems", William Schweber, PHI.

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B.E. SEM VI
601 - MICROCONTROLLER & APPLICATION
1. Micro Controller : The 8051 Architecture:
8051 Micro controller Hardware, Input /Output Pins,Ports,and Circuits, External
Memory, Counter and Timers, Serial Data Input/Output, Interrupts.
2. Basic Assembly Language Programming Concepts :
A Generic Counter, The Mechanics of Programming ,The Assembly Language
Programming Process, Programming Tools and Techniques, Programming the
8051.
3. Moving Data :
Opcodes & Data Exchanges.
4. Logical Operations :
Byte-Level Logical Operations, Bit -Level Logical Operations, Rotate and Swap
Operations.
5. Arithmetic Operations :
Flags, Incrementing and Decrementing, addition, Subtraction, Multiplication and
Division, Decimal Arithmetic.
6. Jump and Call Instructions :
The Jump and Call Program Range, Jump, Calls and Subroutines, Interrupts and
Returns, More Detail on Interrupts.
7. An 8051 Micro controller Design :
A Micro controller Design, Testing the Design, Timing Subroutines, Lookup
Tables for the 8051,Serial Data Transmission.
8. Applications :
Keyboards, Displays, Pulse Measurement, D/A and A/D Conversions, Multiple
Interrupts.
9. Serial Data Communication:
Network Configurations,8051 Data Communication Modes.
The Practical and Term work will be based on the topics covered in the syllabus.
Books :
1. " The 8051 Micro controller, architecture, programming and applications" ,
K.J.Ayala - Penram International Publisher India.
2. “ The 8051 Micro Controller ‘ By: Mazidi & Mazidi.

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602 - THERAPEUTIC TECHNIQUES AND INSTRUMENTATION
1. Dc fibrillator: need and circuit description. Rectangular wave defibrillator,
electrodes used. DC defibrillator with synchronizer, cardioverter. Performance
aspects of DC defibrillator. Implantable defibrillator and defibrillator analyzers.
2. Dialysers: Principle of dialysis, artificial kidney, function and working of dialyser,
parallel flow dialyser, coil hemodialyser, hollow fiber hemodialyser. Performance
analysis of dialysers, membranes used for hemodialysis. Block diagram and
working of hemodialysis machine. Blood leak detector, portable kidney machine
–working and flow diagram.
3. Principle of surgical diathermy. Electrosurgical equipments and techniques.
Electrotomy, fulguration, coagulation, dessication. Electrosurgery units, spark gap
valve, solid-state generator. Construction and working of surgical diathermy
machine, electrodes used. Safety aspects like burns, high frequency current
hazard, and explosion hazard, operating principle of surgical diathermy analyzer.
4. Basic concepts about LASER. LASER coherence. Its principle of operation,
properties, gain medium, pumping mechanism and resonator design. Types of
LASER : pulsed ruby laser, ND YAG laser, argon laser and CO2 laser.
Applications
of laser in
medicine: control of gastric hemorrhage by
photocoagulation, retinal detachment.
5. Short-wave, diapulse , microwave, ultrasonic therapy: circuit description,
application and dosage control. Electrotherapy: diagnosis, electrical stimulation
for pain relief, apparatus and current waveforms, electrodes. Spinal cord
stimulator and cerebral stimulation.
6. Neonatal instrumentation: Incubator : physiological heat balance, heat production
and heat loss methods. Apnea detection. Photo therapy devices.
7. Anesthesia machine: Gas supply and delivery, vapor delivery. Patient breathing
circuit. Complete schematic of anesthesia machine.
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. Handbook of biomedical instrumentation
R.S. Khandpur
PUB: Tata Mcgraw- New Delhi
2. Introduction to biomedical equipment and technology
Carr and Brown PUB: Pearson Education- Asia
3. Medical instrumentation
John Webster.
PUB: John wiley and sons-New York.

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603 - BIOMECHANICS
1.
2.
3.
4.
5.

Mechanics of Blood flow-Heamorheology.
Mechanics of Locomotion: Muscular mechanism, GAIT & Posture.
Mechanics of muscle.
Mechanics of cardiovascular & pulmonary system
Nature and Mechanism of biological control system. Feed back control and its
components. Control of body temperature, Control of Blood pressure, Heart rate.
Control of secretion. Control of movements etc.
6. Biomechanics of solids
7. Fundamentals of fluid mechanics
8. Physiological fluid mechanics
9. Mass transfer
10. Bioheat transfer
11. The interaction of biomaterials and biomechanics
12. Locomotion and muscle biomechanics
The Practical and Term work will be based on the topics covered in the syllabus.
BOOKS :
Introduction to bioengg. - S. A. Berger,Lewis,Goldsmith,Oxferd Press.
Biomechanics
-Sahay & Saxena
Orthopedic Mechanics
-D. N. Ghista & Roaf
604 - COMPUTER NETWORK & DATA COMMUNICATION
1. Introduction
2. data communications: transmission media, fundamental of digital transmission,
digitization and multilevel transmission, terminal devices, wireless
communication, video conferencing
3. The OSI seven layer network model
4. LAN Technologies: overview, hardware, services and operating systems.
5. TCP/IP and the internet: architecture, protocol and datagrams, UDP,TCP, internet
standard services etc.
6. Switching and virtual LAN
7. Communication and network security: cryptography, digital certificate and public
key infrastructure,firewalls, SSL and VPN.

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Books:
1. Networks for computer scientists and engineers – oxford press, Youlu zheng
2. Computer Networks Fourth Edition- Tanenbaum, PHI
3. Data & computer communication- 7th Edition-Stallins-PHI
4. Data Communication- Foruezen-TMH
605 - DIGITAL SIGNAL PROCESSING
1.
2.

3.
4.
5.

6.

7.

8.

Introduction
Discrete-Time Signals and Systems :
Introduction, Discrete-Time Signals, Discrete-Time Systems, LTI Systems,
Properties of LTI Systems, Linear Constant Co-efficient Difference equations,
Frequency domain representation of Discrete-Time Signals & Systems,
Representation of sequences by Fourier Transform, Properties of Fourier
Transform, and correlation of signals Fourier Transform Theorms, Discrete-Time
random signals.
The Z- Transform:
Z-Transform, Properties of ROC for Z-transform, the inverse Z-transform, Ztransform properties.
Sampling of Continuous-Time Signals:
Periodic Sampling, Frequency domain representation of sampling,
Reconstructions of band limited signals from its samples.
Transform Analysis of Linear Time-Invariant System:
Frequency response of LTI system, System functions for systems with linear
constant-coefficient Difference equations, Freq. response of rational system
functions relationship between magnitude & phase, All pass systems,
Minimum/Maximum phase systems, Linear system with generalized.
Structures for Discrete Time Systems:
Block Diagram representation of Linear Constant-Coefficient Difference
equations, Basic Structures of IIR Systems, Transposed forms Basic Structures
for FIR Systems, Overview of finite-precision Numerical effects, Effects of Coefficient quantization, Effect of round off noise in digital filters, Zero input limit
cycles in Fixed-point realizations of IIR filters, Lattice structures.
Filter Design Techniques:
Design of Discrete-Time IIR filters from Continuous-Time filters, Design of FIR
filters by windowing Optimum approximations of FIR filters, FIR equiripple
approximations.
Discrete-Fourier Transform:
Representation of Periodic sequences: The discrete Fourier Series, Properties of
discrete Fourier Series, Fourier Transform of Periodic Signals, Sampling the

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Fourier Transform, The Discrete-Fourier Transform, Properties of DFT, Linear
Convolution using DFT.
9. Computation of Discrete-Fourier Transform:
Efficient Computation of DFT, Goertzel Algorithm, Decimation-in-Time FFT
Algorithms, Decimation-in-Frequency FFT Algorithm.
10. Applications of DSP.
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. “Discrete Time Signal Processing:, Oppeheim, Schafer, Buck Pearson
education publication, 2nd Edition, 2003.
2. “Digital Signal Processing: Principles, Algorithm & Application”, Proakis,
Manolakis, PHI, 2003, 3rd Edition.
3. “Digital Signal Processing: A Computer Based approach”, Sanjit Mitra,
McGrawHill
4. MATLAB user’s guide.

606 – SEMINAR
Student is supposed to select topic on advance area of biomedical engineering and to
carry out a literature survey and based on it prepare and present the seminar.

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B.E. SEM VII
701 - SIMULATION & MODELING OF BIOLOGICAL SYSTEMS
1. Introduction to Physiological control systems, Illustration- example of a physiological
control system. Difference between engineering and physiological control systems.
2. Art of modeling Physiological systems, linear models of physiological systemsdistributed parameters versus lumped parameter models. Principle of superposition.
3. Cardiovascular system modeling and simulation. Theoretical basis, model
development, heart model, circulatory model, computational flow diagram of the
cardiac system, software development.
4. Pulmonary mechanics modeling and simulation. Theoretical basis, model
development, Lung tissue viscoelastance, chest wall, airways-full model of
respiratory mechanics. Pulmonary system software development-computational flow
diagram.
5. Interaction of Pulmonary and Cardiovascular models. Computational flow diagram
for cardiopulmonary software development.
6. Eye movement system and Wetheimer’s saccade eye model. Oculomotor muscle
model. Linear muscle model.
7. Simple models of muscle stretch reflex action, ventilatory control action, Lung
8. Study of steady state analysis of muscle stretch reflex action, ventilatory control
action by MATLAB tools.
9. Study of transient response analysis of neuromuscular reflex model action by
MATLAB tools.
10. Study of frequency domain analysis of linearized model of lungs mechanics,
circulatory control model and glucose insulin regulation model by MATLAB tools.
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. Physiological control systems: Analysis, Simulation and Estimation.
By: Michael C.K.Khoo.
Pub: Prentice Hall of India Pvt. Ltd. New Delhi.
2. Virtual Bioinstrumentation.Biomedical, Clinical and Healthcare applications.
By: Jon B. Olansen and Eric Rosow.
Pub: Prentice Hall PTR. Upper Saddle River, NJ.

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702 - POWER ELECTRONICS
1. Introduction to Power Electronics, Power Diodes, Power Transistors
Overview of Power Electronics, Power Semiconductor Devices, Control Characteristics
of Power Devices, Characteristics and Specification of Switches, Types of Power
Electronic Circuits, Reverse Recovery Characteristics, Types of Power Diodes, Diodes
with RC, RL, LC and RLC Loads, Free wheeling Diodes, Performance Parameters of
Rectifiers, Power BJTs, Power MOSFETs, COOLMOSs, SITs, IGBTs, MOSFET Gate
and BJT Base Drive Circuits, Isolation of Base and Gate Drive Circuits
2. Thyristors
Thyristor Characteristics, Two Transistor model of Thyristor, Thyristor Trun-On,
Thyristor Turn-Off, Types of Thyristors, Series & Parallel Connections of Thyristors,
Gate drive circuits.
3. Controlled Rectifiers
Principal of Phase Controlled Converter, Single Phase Semi Converter, Single Phase Full
Converter, Single Phase Dual Converter, Three Phase Halfwave Converters, Three Phase
Semi Converter, Three Phase Full Converter, Three Phase Dual Converter. (Without
4. Invertors
Principal of Operation of Pulse Width Modulated Inverters, Performance Parameters,
Single Phase Bridge Inverters, Three Phase Inverters, Current Source Inverter, Series
Resonant Inverter, Parallel Resonant Inverter, Class E Resonant Inverter, Multilevel
Inverter Concept, Applications & features of Multilevel Inverter.
5. DC-DC Converters
Principal of Step Down Converter, Principle of Step UP Converter, Performance
Parameters, Converter Classification, Switch Mode Buck, Boost and Buck-Boost
Regulators, Chopper Circuit Design.
6. AC Controllers
Principal of On Off Control, Principal of Phase Control, Cycloconeverters, PWM
Controlled AC Voltage Controllers.
7. Protection of Devices and Circuits
Cooling and Heat Sinks, Snubber Circuits, Reverse Recovery, Supply and Load Side
Transients, Current & Voltage Protection, Electromagnetic Interference.

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8. Power Drives & Applications
Characteristics of DC Motor, Operating Modes of DC Drives, Single Phase DC Drives,
Breaking Schemes of DC-DC Converter Drives, Microcomputer Control of DC Drives,
Control of AC Induction Motors using Voltage, Current and Frequency Control, Stepper
Motor Control, Introduction to FACTS, Introduction to DC Power Supplies & Flyback
Converter, UPS as AC Power Supply, Magnetic Design Considerations.

The Practical and Term work will be based on the topics covered in the syllabus.
Books :
1. Power Electronics Circuits, Devices and Applications by Muhammad H. Rashid,
from PHI and Pearson Education. Third Edition.
2. Power Electronics by M D Singh and K B Khanchandani, TMH Publicaiton
3. Power Electronics by M S Jamil Asghar, PHI Publication
703 - REHABILITATION ENGINEERING
1) INTRODUCTION TO REHABILITATION
Meaning & types of physical, Impairment, Engineering concept in sensory & motor
rehabilitation.
2) ORTHOTICS AND ORTHOPROSTHETICS IN REHABILITATION
Intelligent prosthetic knee, Prosthetic hand, Advance and automated prosthetics and
orthotics, Externally powered and controlled orthotics and prosthetics-FES system,
Restoration of Hand function, Restoration of standing and walking, Hybrid assistive
system(HAS).Myoelectric Hand and Arm prosthesis, Intelligent Hand Prosthesis
(MARCUS ).
3) MOBILITY:
Electronic Travel Applications ( ETA ) :
Path Sounder, Laser Cane, Ultrasonic Torch, Sonic Guide, Light Probes,
Nottingham Obstacle Sensor, Electro-cortical Prosthesis, Electro Roftalam. Polarized
Ultrasonic Travel Aid. Types of wheel chair, Design of wheelchair, Ergonomic
considerations in design of wheelchair, Powered wheelchair, Tricycle, Walkers, Crutches.
4)SENSORY AUGMENTATION AND SUBSTITUATION
Classification of visual impairment, prevention and cure of visual impairment, Visual
augmentation, Tactual vision substitution, auditory substitution and augmentation,
Tactual auditory substitution, Assistive devices for the visually impaired.

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5)MEASUREMENT TOOLS AND PROCESSES IN REHABILITATION
Subjective and Objective measurement methods, Measurement and assessment,
Measurement, objectives and approaches, characterizing human systems and subsystems. Characterizing assistive.
6)COMPUTER APPLICATION IN REHABILITION ENGINEERING
Interfaces in compensation for visual perception, Improvement of orientation and
Mobility.
7)REHABILITATION AIDS FOR MENTALLY IMPAIRED
Sleeping aids, Seating, walking & Postural aids.
The Practical and Term work will be based on the topics covered in the syllabus.
BOOKS :
Rehabilitation Engineering
-Robinson C. J.
Rehabilitation Technology
-Ballabio E.
Text Book of Bio-Medical Engineering
-R. M. Kennedy
Hand Book of Bio-Medical Engineering
-Richard Skalak & Shu Chien
704 - BIOMEDICAL SIGNAL ANALYSIS
Part I: Signal Processing Techniques
1. Random Process
 Stationary and nonstationary random process
 Ergodicity
 Correlation Matrix
 Stochastic Models
 Asymptotic stationary of an autoregressive process
 Selecting the order of the model
2. Eigenanalysis
 Eigenvalue problem
 Properties of Eigenvalue and Eigenvectors
 Eigenfilters
3. Weiner Filter

linear filter
Principle of orthogonality
Minimum mean-squared error .

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Wiener-Hopf Equation
Error-performance surface
Linearly constrained minimum variance filter

4. Linear Prediction
 Forward Linear Prediction
 Backward linear prediction
 Levinson-Durbin Algorithm
 Whitening property of prediction-error filters
 Cholesky Factorization
 Lattice Predictors
 Joint-process estimation
 Burg Algorithm

5. Kalman Filters
 Recursive minimum mean-square estimation
 Kalman filtering problem
 Innovation process
 State estimation using Innovation process
 Filtering
 Initial condition
 Relations between Kalman filter and autoregressive process
 Squared-root kalman filtering
6. Methods of Steepest Descent
 Steepest Descent algorithm
 Stability of the Steepest Descent algorithm
 Transient behavior of the mean-squared error
 Effects of eigenvalue spread and step-size parameter on the Steepest Descent
algorithm

Examples

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Instantaneous frequency measurement
 Stability analysis of the LMS algorithm
 Average tap-weight behavior
 Weight-error correction matrix
 Mean-squared-error behavior
 Transient behavior of the mean-squared error
 Computer results on adaptive first order prediction
 Operation of the LMS in a nonstationary environment
 Normalized LMS algorithm
8. Methods of Least Squares
 Statement of the linear least-squares estimation problem
 Data windowing
 Temporal version of the orthogonality principle
 Minimum sum of error squares
 Normal equation and linear least-squares filters
 Properties of the time averaged correlation matrix
 Properties of least-squares estimation
 FBLP algorithm
 MVDR spectral estimation
9. Standard Recursive Least-Squares Estimation
 Exponentially weighted recursive least-squares algorithm
 Convergence analysis of the RLS algorithm
 Example: Results of computer experiments on adaptive equalization
 Operation of the RLS in a nonstationary environment
 Comparison of the LMS and RLS algorithms
 Relationship between the RLS and kalman filter theory
o
o
o

Part II: Applications to Biomedical Signals

Evoked potential Estimation
o Stimulus Artifact canceling in Somatosensory evoked potentials

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Stimulus Artifact canceling in noncortical somatosensory evoked
potentials
o Ocular Artifact canceling in EEG signals
Cardiovascular System
o Arrhythmia Detection
o QRS Detection
o ECG Signal Analysis
o Heart Rate Variability Analysis
EMG Analysis
EEG Signal Processing
o

The Practical and Term work will be based on the topics covered in the syllabus.
Books
1. S. Haykin, "Adaptive Filter Theory", Prentice-Hall, Inc., Englewood Cliffs, 1996.
2. S. Lim, and A. V. Oppenheim, "Advanced Topics in Signal Processing," Prentice
Hall, Englewood Cliffs, New Jersey, 1988.
3. Papers from the literature.
4. M. Akay, (Edited), "Nonlinear Biomedical Signal Processing: Dynamic analysis
and Modeling," (Vl. II), IEEE Press.
705 - PROJECT PART - I
The student will have to plan his project out and discuss the feasibility of the project with
the faculty members. Faculty member will be their internal guide.
He has to submit a report on what he intends to do and how will he proceed to do his
project. He is supposed to give a complete outline of the project work and submit as term
work in form of the report.
The intended/planned project has to be continued in sem. VIII and complete it as project
Part-II.

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B.E. SEM VIII
801 - MEDICAL IMAGING TECHNOLOGY
Physical Principals of Imaging:
1.

Photons, Electromagnetic Spectrum, Wave Particle Duality; Interactions between
Radiation and matters; Fundamentals of acoustic propagation; Interaction between
sonic beams and matter; concepts of ultrasonic diagnostics.
2. Imaging with X-Rays:
X-ray tube: The generation: Electron-Target Interactions, X-ray emission
spectrum: Characteristic x-ray spectrum, Bremsstrahlung x-ray spectrum, Factors
affecting X-ray Emission Spectrum: Effect of mA, kVp, added filtration; X-ray unit:
generators, filters and grids; Image intensifiers; X-ray detectors: Screen film detector,
Image Intensifier; Radiographic techniques, quality and exposure.
3. X-ray Diagnostic Methods:
Fluoroscopy: Fluoroscopy and Visual Physiology, Image intensifier tube and
Multifield intensification; Angiography: Arterial access, Catheters, Contrast media;
Mammography: Soft tissue radiography, Equipments: Target composition, Filtration
construction of images.
4. Computed Tomography:
Operational modes: First generation scanners, Second, Third, Fourth, Fifth
generation scanners; System components: Gantry, Collimation; High Voltage generators;
Image characteristics: Image matrix, CT numbers; Image reconstruction; Image Quality:
Spatial resolution, Contrast resolution, System noise, Linearity, Spatial Uniformity.
5. Imaging with Ultrasonography:
Piezoelectric effect; Ultrasonic transducers: Mechanical and Electrical matching,;
The characteristics of transducer beam: Huygens principle, Beam profiles, Pulsed
ultrasonic filed, Visualization and mapping of the Ultrasonic field; Doppler effectDoppler methods; Pulse echo systems[Amplitude mode, Brightness mode, Motion mode
&Constant depth mode]; Tissue characterization: velocity, Attenuation or absorption,
Scattering.
6. Developments in Ultrasound technique:
Color Doppler flow imaging: CW Doppler imaging device, Pulsed Doppler
imaging system, clinical applications; Intracavity imaging: Design of the Phased array
probe, Trans oesophageal, Tannsvaginal or Transrectal scanning; Ultrasound contrast
media:

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Utilization of micro air bubbles, galactose microparticles and albumin encapsulated
microairbubbles; 3-D image reconstruction; 2-D echo cardiography
7. Biological effects of Radiation and Ultrasound and its protection:
Modes of Biological effects: Composition of the body and Human response to
Dose-response relationships; Time variance of radiation exposure; Thermal / Nonthermal
effects due to cavitation in ultrasound fields; Designing of radiation protections and its
procedures.
Introduction to Magnetic Resonance Imaging, Radionuclide Imaging, Longitudinal
section Tomography, Single Photon Emission Computed Tomography, Positron Emission
Tomography.
9. Nuclear medical imaging: Radionuclides. Interaction of photons with matter. Data
acquisition. Imaging: image quality, equipment. Clinical use. Biological effects and
safety.
10.Infrared imaging: Infrared photography. Transillumination. Infrared imaging. Liquid
crystal thermography. Microwave thermography.
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. Principles of Medical Imaging.
2. By: K. Kirk Shung, Michael B. Smith, Benjamin Tsui.
Pub:
4. By: Stewart C. Bushong. Pub: Mosby: A Harcourt Health Sciences
Company..
5. Quality Management: In the Imaging Sciences.
6. By: Jeffery Papp.
Pub: Mosby: A Harcourt Health Sciences Company
7. Fundamentals of medical imaging:
8. Paul suetens. Pub: Cambridge university press
9. Introduction to biomedical imaging
10. Andrew Webb.
Pub: IEEE press series : Wiley Interscience.
11. The Physics of medical imaging
12. Steve Webb. Pub: Institute of Physics Publishing, Bristol and
13. Fundamentals of digital image Processing
14. Jain A K.
Pub: Prentice Hall
15. Digital Image Processing 2nd edition 1987.
16. Gonzalec R. C.
Pub: Addison Wesley and P Wintz.

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
Gandhinagar-382028.
Tel: (079)29289540 ; Fax : (079)23243708
Email: [email protected]
802 - FUZZY LOGIC & NEURAL NETWORK
FUZZY LOGIC
1. Introduction. Foundation of Fuzzy sytems; Fuzzy systems at work; Fuzzy system
design.
2. Crisp us. Fuzzy sets; Fuzzy sets to fuzzy events. Fuzzy logic. Practical fuzzy
measures. Fuzzy set operations; properties of fuzzy sets, Fuzzification techniques.
Relational inference. Compositional inference. Linguistic variables and logic
operators. Inference using fuzzy variables. Fuzzy implication.
3. Fuzzy systems and algorithms, Defuzzication. Adaptive fuzzy sytems algorithms.
Expert systems vs fuzzy inference engines. Basic fuzzy inference algorithm. Overall
algorithm. Input data processing. Evaluating antecedent fuzzy variables. Left hand
side computations; Right hand side computations. Output processing.
4. Fuzzy sytem design and its elements. Design options, processes and background
requirements. Knowledge acquisition. Principle of fuzzy inference design criteria.
Systems ontology and problem types. Useful supporting design tools.
5. Fuzzy sytems: Fuzzy information; Fuzzy neural networks; Fuzzy approaches for
supervised learning networks. Fuzzy generalization of unsupervised learning
methods. Reasoning with uncertain information. Preprocessing and postprocessing
using fuzzy techniques. Application in biomedical engineering.
6. Hybrid systems: Knowledge based and data based approaches; neural network
component; time series data; Use of complex data structures; Design methodology;
Applications; Automatic ECG analyzer. Diagnosis of heart disease.
Neural Network:
1. Introduction : What is a Neural Network? , Structural Levels of Organization in the
Brain ,Models of a Neuron ,Network Architectures ,Knowledge Presentation ,Artificial
Intelligence and Neural Network
2. Learning Process:Error-Correction Learning ,Hebbian Learning ,Competitive
Learning ,Boltzman Learning ,The Credit Assignment Problem ,Supervised Learning
Reinforcement Learning ,Unsupervised Learning ,Adaptation and Learning ,Statistical
Nature of Learning Process
3. Self Organizing Systems1: Hebbian Learning:Some Intuitive Principles of Self
Organization ,Self Organized Feature Analysis ,Discussion ,Principal Component
Analysis ,A linear Neuron Model as Maximum Eigenfilter ,Self Organized Principal
Component Analysis ,Adaptive Principal Component Analysis Using Lateral
Inhibition ,Two Class of PCA Algorithm ,How Useful is Principal Component Analysis?

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
Gandhinagar-382028.
Tel: (079)29289540 ; Fax : (079)23243708
Email: [email protected]

4. Temporal Processing: Spatio-Temporal Models of Neuron,FIR Multilayer
Perceptron,Temporal Back-propagation Learning,Temporal Back-propagation Learning
with Adaptive Time Delays,Back-propagation Through Time,Real-Time Recurrent
Networks,Real-Time Nonlinear Adaptive Prediction of Nonstationary signals,Partially
Recurrent Network .
5.
Neurodynamics:
Dynamical
Systems,Stability
of
Equilibrium
States,Attractors ,Strange Attractors and Chaos ,Neurodynamical Models ,Manipulation
of Attractors as a Recurrent Network Paradigm ,Dynamics of Hopfield Models ,The
Cohen Grossberg Theorem,A Hopfield Model as a Content-Addressable Memory ,BrainState-in-a-Box Model ,Recurrent Back-propagation .
The Practical and Term work will be based on the topics covered in the syllabus.
Books:
1. Fuzzy systems Design Principles.
By: Riza C. Berkan and Sheldon L. Trubateh.
Pub: Standard Publishers and Distributors. Delhi.
2. Fuzzy Control Systems.
By: Abraham Kandel and Gideon Langholz.
Pub: CRC Press- Boca Raton.
3. Biomedical engineering handbook.
By: Joseph D Bronzino
Pub: CRC Press – IEEE Press
4. S. Haykin, Neural Networks: A comprehensive foundation, NJ: Prentice-Hall,
1999
803 -HOSPITAL MANAGEMENT
Hospital Organization:
1. Various Aspects Of Hospital Services:
2. Outdoor Patient, Indoor, Supportive, Emergency, Dietary, Nursing, Medical
Supplies Etc.
4. Typical Layout of a Hospital Shoving Various Departments.
5. Organization of Various Clinical Departments.
6. Organization Of Bio-Medical Engineering Department
7. Duties & Responsibilities Activity Planning Dept Layout, Staff Deployment ,
Equipment Deployment , Tools Requirement , Planning Of Document Such As

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
Gandhinagar-382028.
Tel: (079)29289540 ; Fax : (079)23243708
Email: [email protected]
Operating Manual, Ckt Diagrams, Data-Book, Preventive Maintenance Schedule,
Data Bases Of Equipment Supply, Tech. Specification Of Equipments, List Of Users,
Spare Part List.
8. Patient Care Services Recovery Room , ICU, ICCU, PICU,NICU
9. Support Services: Central Sterilization Service, Kitchen, Laundry Etc.
10. Engineering Services:
11. Organization Of Operation Theatre
12. Blood Bank
13. Physiotherapy & Rehabilitation Center
14. Others
1.
2.
3.
4.
5.
6.
7.
8.

Hospital Management:
General Management Functions: Planning, Co-Coordinating, Monitoring,
Controlling, Decision Marking, Motivation
Management Information System For Hospital : Information gathering &
acquisition, flow, storage, processing, hospital statistics, use of computer in
database management.
Material Management
Personnel Management
Quality Management & Audit
Maintenance Management
Waste Management
Cost Control & Financial Management
Books:
1. Principles of Hospital Administration & Planning
--Dr. B.M. Sakharkar, J.P.Brothers
--A B Srinivasan ,Response Book
--Clewelyn-Davis , J.P.Brothers
4.Human Resource Management In Hospital
--R.C.Coyal,Phi New Delhi
--Shakti Gupta ,J.P.Brothers

GOVERNMENT ENGINEERING
COLLEGE
Sector –28, Nr.Pashujaivik,
Gandhinagar-382028.
Tel: (079)29289540 ; Fax : (079)23243708
Email: [email protected]

804 - PROJECT PART- II
The intended/ planned project has to be continued in Sem. VIII and complete it as project
Part-II.

Official seal of college

Seal and signature
of principal

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