what is hypertensice disease in pregnancy..how to manage it..
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HYPERTENSIVE DISEASE IN PREGNANCY
Definition:
BP of 140/90 mmHg or more taken on 2 occasion at least 4 hour apart; OR An increase in systolic BP of 30 mmHg or/and diastolic BP of 15 mmHg compared to pre-pregnancy level
Single reader of Diastolic BP more than 110mmHG.
1) GESTATIONAL HYPERTENSION
Is hypertension after 20th week of gestation in a previously normotensive woman x proteinuria Condition return to norm within 6 weeks after labour 2) PRE- ECLAMPSIA
3) CHRONIC HYPERTENSION
Presence of hypertension of at least 140/90 mmHg before 20th week of pregnancy or beyond 6 weeks postpartum.
Includes essential & secondary hypertension. 4) CHRONIC HYPERTENSION WITH SUPERIMPOSED PRE-ECLAMPSIA
Development of pre-eclampsia in patient with pre-existing hypertension Criteria used should include: – worsening of hypertension
–
proteinuria
Management:
Antenatal: 1. Identify risk factor and observe BP:
-past history or family history of pre eclampsia or eclampsia -excessive weight gain 2. Physical examination,urinanlysis,BP
3. Confirm Diagnosis:
Mild PIH Outpatient
Severe PIH,PE Admission
Outpatient management:
Antenatal clinic visit: – every 4 weeks – every 2 weeks if x on treatment,norm biophysical profile,good fetal growth if on treatment
Tests: – urinalysis (protein) – BP – SFH and liquor vol. – BUSE,FBC,Serum uric acid
Fetal surveillance: US monthly,FKC Inpatient/Admission: BP every 4 hrs SFH and liquor vol. Daily PE chart,urine protein FBC,BUSE,serum uric acid LFT,Coagulation profile(if suspected HELLP) I/O chart Fetal surveillance: – FKC,CTG,US v v Antihypertensive agents only used if DBP>100mmHg.(aim: maintain 90-100mmHg) Dexamethasone if early delivery expected (<34weeks)
CTG monitoring Shortened 2nd stage- assisted delivery,episiotomy X syntometrime/ergometrine! Use Syntocinon 10 units Postpartum management Beware of Sx of IE and pulmonary oedema BP monitoring – – 1/2hourly monitoring for at least 2 – 4hours before sending to postnatal ward 4 hourly monitoring in the ward for 24 – 48hours before discharge Antihypertensive should be continued and stopped later on postnatal review. (methydopa discontinueà can cz postpartum depression)
I/O chart Daily urine albumin,PE chart Criteria for discharge:
Asymptomatic BP< 140/90mmHg Reflexes not brisk Urine albumin- nil Mono-antihypertensive therapy v Review patient in 2 weeks and 6 weeks
ANTI-HYPERTENSIVE MEDICATION
AIM: to keep diastolic BP between 90-100mmHg!
ECLAMPSIA
Pregnancy induced hypertension with generalized tonic clonic fits OBSTETRICAL EMERGENCY! Aim of management: – Control convulsion
–
Control blood pressure
–
Stabilize patient
-
Delivery
Management
4 subsections:
1) Resuscitation and general management
2) Anticonvulsive therapy
3) Antihypertensive therapy
4) Delivery
(A) Resuscitation and General 1. Left lateral position,2 IV lines
2. Maintain airway,O2 mask
3. Abort fit by- MgSO4 loading dose= 4g IV bolus over 10-15 min
= 5g IM each buttock(10g)
* (1 amp:5ml – 2.5g MgSO4)
* 8ml- 4g (dilute in 12ml Nacl waterà 20ml)
OR
Diazepam IV 10mg bolus (1-2min)
4. After fit aborted- GXM,Coagualtion profile,renal profile,platlet count.
5. Asses level of consciousness & neurological status
6. Closely monitor V/S- BP,PR,SPO2,RR,I/O chart
(B) Anticonvulsive therapy 1. MgSO4 à Maintainance dose: *IV infusion of 1g/hour
* 5ml MgSO4 + 45ml 5%Dextrose sol.
à Infuse at 20ml/hour( syringe pump)
OR
* 10ml MgSO4 in 500ml D5% at 33 dpm (drips)
ü
Duration: – continue for 24hours after last fit or after delivery
ü
Monitoring for MgSO4 therapy:
1.Investigations-
BUSE,FBC Serum Ca2+,Mg Renal function test (urea,uric acid,creatinine) Coagulation profile UFEME ECG GXM 2. STOP !!! If present signs of Mg toxicity: