Melanoma _ Lentigo Maligna (Kanski)

1
Lentigo maligna & Melanoma (Kanski)
Melanoma jrg timbul pd palp tp bpotensi lethal. Wlp’ pigmentasi a/
tnd khas melanoma klt, ½ dr melanoma palp a/ non-pigmented & ini
dpt myb kslt’ dlm D/. G/ yg mnunj melanoma : recent onset lesi
pigmented, prbh’ pd existing pigmented lesion, margin irregular, btk
asimetris, prbh’ w / a n’ multiple color, & diameter > 6 mm.

Lentigo maligna
(maligna in situ, intradermal melanoma, & Hutchinson freckle) a/
kead jrg yg timbul pd klt sun-damaged pd org tua. Prbh’ maligna dpt
tjd, dgn infiltrasi dermis.
1.PA : proliferasi i/dermal dari melanosit atipikal bbtk spindle yg
mganti basal layer dari epidermis.
2.Tnd :
-Slowly expanding pigmented macule dgn tepi irregular.
(lentigo maligna)

-Pnebalan nodular & drh pigmentasi irregular : sgt mnunj transformasi
maligna.
(melanoma yg timbul dr
lentigo maligna)

2
3.Th/ : b/ eksisi.

Melanoma
1.PA : melanosit atipikal bsr di dlm dermis.
2.Tnd :
a.Superficial spreading melanoma : khas : plak dgn batas irregular &
variable pigmentasi.
(Melanoma – superficial
spreading melanoma)

b.Nodular melanoma : khas : blue-black nodul dikllgi dgn klt N.
(nodular melanoma)

3.Th/ b/ wide excision & dpt tmsk removal KGB lokal.