Spinal Surgery Devices Market

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Spinal Surgery Devices Market - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 Published: October 2011 Price: $ 3500

GBI Research‟s report, “Spinal Surgery Devices Market - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017” provides key data, information and analysis on the global aesthetic Devices market. The report provides market landscape, competitive landscape and market trends information on two spinal surgery devices market categories – spinal fusion devices and spinal non-fusion devices. The report provides comprehensive information on the key trends affecting these categories, and key analytical content on the market dynamics. The report also reviews the competitive landscape with major acquisitions and mergers in the last three years and a detailed analysis of the pipeline products in each category. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Research‟s team of industry experts. Scope • The report analyses the Spinal Surgery Devices Market along with the major forces driving the current market and the potential challenges that can restrain the growth. The scope of the report includes: • Key geographies covered include the US, Canada, the UK, Germany, France, Italy, Spain, Japan, China, India, Australia and Brazil. • Market size data for two spinal surgery devices market categories – spinal fusion devices and spinal non-fusion devices • Annualized market revenues data, forecast forward for 7 years to 2017. Company share data for 2010. • Qualitative analysis of key market trends for global spinal surgery devices market. • Qualitative analysis of market drivers and restraints by each category within the spinal surgery devices market. • The report also covers information on the leading market players, the competitive landscape, and the leading technologies. Reasons to Buy The report will enhance your decision making capability. It will allow you to • Develop business strategies by understanding the trends and developments that are driving the spinal surgery devices market globally. • Design and develop your product development, marketing and sales strategies.

• Exploit M&A opportunities by identifying market players with the most innovative pipeline. • Develop market-entry and market expansion strategies. • Identify key players best positioned to take advantage of the emerging market opportunities. • Exploit in-licensing and out-licensing opportunities by identifying products, most likely to ensure a robust return. • What‟s the next being thing in the spinal surgery devices market landscape? – Identify, understand and capitalize. • Make more informed business decisions from the insightful and in-depth analysis of the global spinal surgery devices market and the factors shaping it. Table Of Contents 1 Table Of Contents 1 Table Of Contents 2 1.1 List of Tables 8 1.2 List of Figures 11 2 Executive Summary 14 2.1 Global Spinal Surgery Devices Market is Forecast to Reach $12.6 Billion by 2017 14 2.2 The US will Continue to be the Biggest Market for Spinal Surgery Devices 15 2.3 Medtronic Dominates the Global Market for Spinal Surgery Devices 16 2.4 Elderly Population to Drive Growth of Spinal Surgery Devices Market 17 2.5 Technological Innovations to Increase Adoption of Spinal Procedures in the Future 17 3 Introduction 18 3.1 GBI Research Guidance 18 4 Disease Overview 20 4.1 Degenerative Disc Disease 20 4.2 Spinal Stenosis 20 4.3 Spondylolisthesis 20 5 Device Overview 21 5.1 Spinal Fusion Devices 21 5.1.1 Pedicle Screw Systems 21 5.1.2 Interbody Cages 22 5.1.3 Spinal Plating Systems 22 5.2 Spinal Non-Fusion Devices 22 5.2.1 Dynamic Stabilization 22 5.2.2 Artificial Disc Replacement 22 5.2.3 Interspinous Process Decompression (IPD) Devices 23 6 Spinal Surgery Devices: Market Characterization 24 6.1 Spinal Surgery Devices Market, Global, Revenue ($bn), Forecast, 2003–2010 24 6.2 Spinal Surgery Devices Market, Global, Revenue ($bn), Forecast, 2010–2017 25 6.3 Spinal Surgery Devices Market, Company Share (%), Global, 2010 26 6.4 Spinal Surgery Devices, Market Trends 28 6.4.1.1 Minimally Invasive Lateral Interbody Fusion to Drive the Future Growth of the Spinal Surgery Devices Market in the Future 28 6.4.1.2 3-D Image Guided Spine Surgery to Drive the Growth of the Spinal Surgery Devices Market in the Future 29 6.5 Spinal Surgery Devices, Market Dynamics 30

6.5.1 Market Drivers 30 6.5.1.1 Increasing Number of Spinal Fusion Procedures to Drive the Growth of Spinal Surgery Devices in the Future 30 6.5.1.2 Elderly Population to Drive the Growth for Spinal Surgery Devices Market in the Future 31 6.5.1.3 Increase in the Adoption of Minimally Invasive Spinal Surgery Devices to Drive the Market Growth 33 6.5.1.4 Technological Innovations to Increase the Adoption of Spinal Surgery in the Future 34 6.5.2 Market Restraints 34 6.5.2.1 Growth of Alternative Technologies to Restrain the Growth of Spinal Surgery Devices 34 6.5.2.2 Lack of Skilled Surgeons will Negatively Impact the Market for Spinal Surgery Devices 35 7 Spinal Surgery Devices Market: Segment Analysis and Forecasts 38 7.1 Spinal Fusion Devices Market, Global, Revenue ($bn), Forecast, 2003–2010 38 7.2 Spinal Fusion Devices Market, Global, Revenue ($bn), Forecast, 2010–2017 39 7.3 Spinal Fusion Devices, Market Dynamics 40 7.3.1 Market Drivers 40 7.3.1.1 US Food and Drug Administration (FDA) Reclassification of Spinal Fusion Devices to Continue to Drive the Growth of the Spinal Fusion Devices Market 40 7.3.1.2 Increase in Medicare Reimbursement for Spinal Procedures to Drive the Spinal Fusion Devices Market 41 7.3.2 Market Restraints 42 7.3.2.1 Reimbursement Challenges to Continue to Limit the Growth of Minimally Invasive Spinal Fusion Procedures 42 7.3.2.2 Potential Complications and Patient Discomfort Associated with Spinal Fusion Procedures to Slow Down the Growth 42 7.4 Spinal Non-Fusion Devices Market, Global, Revenue ($m), Forecast, 2003–2010 43 7.5 Spinal Non-Fusion Devices Market, Global, Revenue ($m), Forecast, 2010–2017 44 7.6 Spinal Non-Fusion Devices, Market Dynamics 45 7.6.1 Market Drivers 45 7.6.1.1 Technological Advantages over Spinal Fusion Devices to Drive the Growth of the Spinal Non-Fusion Devices Market 45 7.6.2 Market Restraints 46 7.6.2.1 Unfavorable Reimbursement Policies and Lack of Clinical Evidence are the Major Restraints for the Growth of Spinal Non-Fusion Devices Market 46 8 Spinal Surgery Devices Market, Revenue ($m), by Country, Revenue ($m), Historic and Forecast, 2003–2017 47 8.1 Spinal Surgery Devices Market, The US, Revenue ($m), Historic, 2003–2010 47 8.2 Spinal Surgery Devices Market, The US, Revenue ($m), Forecast, 2010–2017 49 8.3 Spinal Surgery Devices Market, Canada, Revenue ($m), Historic, 2003–2010 51 8.4 Spinal Surgery Devices Market, Canada, Revenue ($m), Forecast, 2010–2017 52 8.5 Spinal Surgery Devices Market, The UK, Revenue ($m), Historic, 2003–2010 54 8.6 Spinal Surgery Devices Market, The UK, Revenue ($m), Forecast, 2010–2017 56 8.7 Spinal Surgery Devices Market, France, Revenue ($m), Historic, 2003–2010 57 8.8 Spinal Surgery Devices Market, France, Revenue ($m), Forecast, 2010–2017 59 8.9 Spinal Surgery Devices Market, Germany, Revenue ($m), Historic, 2003–2010 60 8.10 Spinal Surgery Devices Market, Germany, Revenue ($m), Forecast, 2010–2017 62 8.11 Spinal Surgery Devices Market, Italy, Revenue ($m), Historic, 2003–2010 63

8.12 Spinal Surgery Devices Market, Italy, Revenue ($m), Forecast, 2010–2017 65 8.13 Spinal Surgery Devices Market, Spain, Revenue ($m), Historic, 2003–2010 66 8.14 Spinal Surgery Devices Market, Spain, Revenue ($m), Forecast, 2010–2017 68 8.15 Spinal Surgery Devices Market, Japan, Revenue ($m), Historic, 2003–2010 70 8.16 Spinal Surgery Devices Market, Japan, Revenue ($m), Forecast, 2010–2017 71 8.17 Spinal Surgery Devices Market, China, Revenue ($m), Historic, 2003–2010 72 8.18 Spinal Surgery Devices Market, China, Revenue ($m), Forecast, 2010–2017 74 8.19 Spinal Surgery Devices Market, Australia, Revenue ($m), Historic, 2003–2010 75 8.20 Spinal Surgery Devices Market, Australia, Revenue ($m), Forecast, 2010–2017 77 8.21 Spinal Surgery Devices Market, India, Revenue ($m), Historic, 2003–2010 78 8.22 Spinal Surgery Devices Market, India, Revenue ($m), Forecast, 2010–2017 80 8.23 Spinal Surgery Devices Market, Brazil, Revenue ($m), Historic, 2003–2010 81 8.24 Spinal Surgery Devices Market, Brazil, Revenue ($m), Forecast, 2010–2017 83 9 Spinal Surgery Devices, Market Opportunities and Risk Evaluation 85 9.1.1.1 Market Opportunities 85 9.1.1.2 Risks 86 10 Key Market Participants and Internal Factor Analysis 87 10.1 Medtronic, Inc. 87 10.1.1 Key Marketed Products 87 10.1.2 Pipeline Products 87 10.1.2.1 Internal Factor Analysis 87 10.1.2.2 Strengths 88 10.1.2.3 Weaknesses 88 10.2 DePuy, Inc. 89 10.2.1 Key Marketed Products 89 10.2.2 Pipeline Products 90 10.2.2.1 Internal Factor Analysis 90 10.2.2.2 Strengths 90 10.2.2.3 Weaknesses 91 10.3 Synthes, Inc. 91 10.3.1 Key Marketed Products 91 10.3.2 Pipeline Products 92 10.3.2.1 Internal Factor Analysis 92 10.3.2.2 Strengths 92 10.3.2.3 Weakness 93 10.4 Stryker Corporation 93 10.4.1 Marketed Products 93 10.4.2 Pipeline Products 93 10.4.2.1 Internal Factor Analysis 94 10.4.2.2 Strengths 94 10.4.2.3 Weaknesses 94 10.5 NuVasive Inc. 95 10.5.1 Key Marketed Products 95 10.5.2 Pipeline Products 95 10.5.2.1 Internal Factor Analysis 96 10.5.2.2 Strengths 96 10.5.2.3 Weaknesses 97 11 Spinal Surgery Devices Market: Pipeline Analysis 98 11.1 Artificial Disc Replacement Devices, List of Pipeline Products 98 11.1.1 Artificial Disc Replacement Market, Key Pipeline Products 99

11.1.1.1 Flexicore Lumbar Artificial Disc: Stryker Corporation 99 11.1.1.2 Mobidisc- LDR Holding Corporation 100 11.1.1.3 M6-C Artificial Cervical Disc: Spinal Kinetics Inc. 102 11.1.1.4 NuNec Cervical Arthroplasty Device: Pioneer Surgical Technology, Inc 103 11.2 Dynamic Stabilization Devices, List of Pipeline Products 105 11.2.1 Dynamic Stabilization Market, Key Pipeline Products 105 11.2.1.1 Wallis System: Zimmer Holdings, Inc. 105 11.2.1.2 Dynesys Dynamic Stabilization System: Zimmer Holdings, Inc. 107 11.2.1.3 Lumbar Intervertebral Disk Stabilization: PARAMOUNT SURGICALS 109 11.3 Interspinous Process Decompression (IPD) Devices, List of Pipeline Products 110 11.3.1 Interspinous Process Decompression (IPD) Devices Market, Key Pipeline Products 111 11.3.1.1 Aperius PercLID: Medtronic, Inc. 111 11.3.1.2 Coflex: Paradigm Spine, LLC 112 11.3.1.3 FLEXUS Inter-Spinous Spacer: Globus Medical, Inc 114 11.3.1.4 In-Space: Synthes, Inc. 115 11.4 Interbody Cages, List of Pipeline Products 117 11.4.1 Interbody Cages Market, Key Pipeline Products 117 11.4.1.1 CBK-PEEK Cervical Cage: Alphatec Holdings, Inc. 117 11.4.1.2 PCB: Alphatec Holdings, Inc. 118 11.4.1.3 KLA-PEEK lordotic ALIF cage: Scient'x USA 120 11.5 Pedicle Screw Systems, List of Pipeline Products 122 11.5.1 Pedicle Screw Systems Market, Key Pipeline Products 122 11.5.1.1 Elaspine: SpineLab AG 122 11.5.1.2 G5 Posterior Screw System: Medtronic, Inc. 124 11.5.1.3 HA Coated TSRH 3Dx Osteogrip Screws: Medtronic, Inc. 124 11.5.1.4 OsseoFix Spinal Fracture Reduction System: Alphatec Holdings, Inc. 124 11.6 Spinal Plating Systems, List of Pipeline Products 125 11.6.1 Spinal Plating Systems Market, Key Pipeline Products 125 11.6.1.1 Cervical Laminoplasty Plate System: CG Surgical Ltd 125 11.6.1.2 LYRA: Alphatec Holdings, Inc. 126 11.6.1.3 Pioneer Anterior Cervical Plate: Bonovo Orthopedics, Inc. 126 12 Spinal Surgery Devices Market: M&A Landscape 128 12.1 Key Acquisitions 128 12.1.1 Johnson & Johnson Enters Into an Agreement to Acquire Synthes 128 12.1.1.1 Deal Overview 128 12.1.1.2 Deal Rationale 129 12.1.2 Integra LifeSciences Acquires SeaSpine 129 12.1.2.1 Deal Overview 130 12.1.2.2 Deal Rationale 130 12.1.3 Alphatec Spine Completes Acquisition of Scient'x Groupe 130 12.1.3.1 Deal Overview 130 12.1.3.2 Deal Rationale 131 12.1.4 NuVasive Acquires Cervitech 131 12.1.4.1 Deal Overview 131 12.1.4.2 Deal Rationale 131 12.1.5 Zimmer Holdings Acquires Abbott Spine from Abbott Laboratories 131 12.1.5.1 Deal Overview 132 12.1.5.2 Deal Rationale 132 12.1.6 Integra LifeSciences Holdings Acquires Theken Spine 132

12.1.6.1 Deal Overview 132 12.1.6.2 Deal Rationale 133 12.1.7 Zimmer Holdings Acquires Endius 133 12.1.7.1 Deal Overview 133 12.1.7.2 Deal Rationale 133 12.1.8 Medtronic Acquires Kyphon 133 12.1.8.1 Deal Overview 134 12.1.8.2 Deal Rationale 134 12.1.9 MiMedx Acquires SpineMedica 134 12.1.9.1 Deal Overview 134 12.1.9.2 Deal Rationale 135 12.1.10 Orthofix Acquires Blackstone Medical 135 12.1.10.1 Deal Overview 135 12.1.10.2 Deal Rationale 135 13 Appendix 136 13.1 Definitions 136 13.1.1 Spinal Surgery Devices 136 13.1.1.1 Spinal Fusion Devices 136 13.1.1.2 Spinal Non-Fusion Devices 136 13.2 Acronyms 137 13.3 Sources 137 13.4 Research Methodology 138 13.4.1 Secondary Research 138 13.4.2 Primary Research 139 13.4.3 Models 139 13.4.4 Forecasts 140 13.4.5 Expert Panels 140 13.5 Contact Us 140 13.6 Disclaimer 140 List of Tables Table 1: Spinal Surgery Devices Market, Global, Revenue ($bn), 2003–2010 24 Table 2: Spinal Surgery Devices Market, Global, Revenue ($bn), 2010–2017 25 Table 3: Spinal Surgery Devices Market, Global, Company Share (%), Revenue ($m), 2010 26 Table 4: Spinal Fusion Procedures („000s), Global, 2006–2011 30 Table 5: Percentage of People Aged 65 Years and Above in Total Adult Population, By Country (%), 1980–2050 32 Table 6: Number of Orthopedic Surgeons in the US, 2002–2010 35 Table 7: Orthopedic Surgeons by Age Group, The US, 2010 36 Table 8: Spinal Fusion Devices Market, Global, Revenue ($bn), 2003–2010 38 Table 9: Spinal Fusion Devices Market, Global, Revenue ($bn), 2010–2017 39 Table 10: Medicare Reimbursement for Spinal Fusion Procedures, 2010 41 Table 11: Spinal Non-Fusion Devices Market, Global, Revenue ($m), 2003–2010 43 Table 12: Spinal Non-Fusion Devices Market, Global, Revenue ($m), 2010–2017 44 Table 13: Spinal Surgery Devices Market, The US, Revenue ($m), 2003–2010 47 Table 14: Spinal Surgery Devices Market, The US, Revenue ($m), 2010–2017 49 Table 15: Spinal Surgery Devices Market, Canada, Revenue ($m), 2003–2010 51 Table 16: Spinal Surgery Devices Market, Canada, Revenue ($m), 2010–2017 53 Table 17: Spinal Surgery Devices Market, The UK, Revenue ($m), 2003–2010 55

Table 18: Spinal Surgery Devices Market, UK, Revenue ($m), 2010–2017 57 Table 19: Spinal Surgery Devices Market, France, Revenue ($m), 2003–2010 58 Table 20: Spinal Surgery Devices Market, France, Revenue ($m), 2010–2017 59 Table 21: Spinal Surgery Devices Market, Germany, Revenue ($m), 2003–2010 61 Table 22: Spinal Surgery Devices Market, Germany, Revenue ($m), 2010–2017 62 Table 23: Spinal Surgery Devices Market, Italy, Revenue ($m), 2003–2010 64 Table 24: Spinal Surgery Devices Market, Italy, Revenue ($m), 2010–2017 65 Table 25: Spinal Surgery Devices Market, Spain, Revenue ($m), 2003–2010 67 Table 26: Spinal Surgery Devices Market, Spain, Revenue ($m), 2010–2017 69 Table 27: Spinal Surgery Devices Market, Japan, Revenue ($m), 2003–2010 70 Table 28: Spinal Surgery Devices Market, Japan, Revenue ($m), 2010–2017 71 Table 29: Spinal Surgery Devices Market, China, Revenue ($m), 2003–2010 73 Table 30: Spinal Surgery Devices Market, China, Revenue ($m), 2010–2017 74 Table 31: Spinal Surgery Devices Market, Australia, Revenue ($m), 2003–2010 76 Table 32: Spinal Surgery Devices Market, Australia, Revenue ($m), 2010–2017 77 Table 33: Spinal Surgery Devices Market, India, Revenue ($m), 2003–2010 79 Table 34: Spinal Surgery Devices Market, India, Revenue ($m), 2010–2017 80 Table 35: Spinal Surgery Devices Market, Brazil, Revenue ($m), 2003–2010 81 Table 36: Spinal Surgery Devices Market, Brazil, Revenue ($m), 2010–2017 83 Table 37: Medtronic, Key Marketed Products, Applications, Features and Benefits, 2011 87 Table 38: Medtronic, Inc., Pipeline Products, 2011 87 Table 39: DePuy, Inc., Key Marketed Products, Applications, Features and Benefits, 2010 89 Table 40: DePuy, Inc., Pipeline Products, 2011 90 Table 41: Synthes, Inc., Key Marketed Products, Applications, Features and Benefits, 2010 91 Table 42: Synthes, Inc., Pipeline Products, 2011 92 Table 43: Stryker Corporation, Marketed Products, Applications, Features and Benefits, 2010 93 Table 44: Stryker Corporation, Pipeline Products, 2011 93 Table 45: NuVasive Inc., Key Marketed Products, Applications, Features and Benefits, 2010 95 Table 46: NuVasive Inc., Pipeline Products, 2011 95 Table 47: Artificial Disc Replacement Devices Market, List of Pipeline Products, Global, 2010 98 Table 48: Flexicore Lumbar Artificial Disc, Product Status 99 Table 49: Prospective, Randomized Trial of Metal-on-Metal Artificial Lumbar Disc Replacement: Initial Results for Treatment of Discogenic Pain 99 Table 50: Mobidisc, Product Status 100 Table 51: Study To Evaluate Mobidisc - European Clinical Results 101 Table 52: M6-C Artificial Cervical Disc, Product Status 102 Table 53: Feasibility Study To Evaluate the Initial Safety and Clinical Use of a M6-C Artificial Cervical Disc 102 Table 54: NuNec Cervical Arthroplasty Device, Product Status 103 Table 55: NuNec: A PEEK-on-PEEK Cervical Arthroplasty System: In Clinical Perspective 104 Table 56: Dynamic Stabilization Devices Market, List of Pipeline Products, Global, 2010 105 Table 57: Wallis System, Product Status 105 Table 58: Wallis Interspinous Prospective Open Study In Degenerative Lumbar Segment

106 Table 59: Clinical Outcomes of Patients With The Wallis System: Two Year Follow-Up International Study 106 Table 60: Dynesys Dynamic Stabilization System, Product Status 107 Table 61: A Biomechanical Assessment of the DYNESYS Stabilization System Using Radiostereometric Analysis 108 Table 62: Lumbar Intervertebral Disk Stabilization, Product Status 109 Table 63: A Multi-Center Randomized Trial to Evaluate Lumbar Intervertebral Disk Stabilization Using Another Disk Device as a Control 109 Table 64: Interspinous Process Decompression (IPD) Devices, List of Pipeline Products, Global, 2010 110 Table 65: Aperius PercLID, Product Status 111 Table 66: A Multicenter Prospective Randomized Controlled Clinical Trial to Evaluate the Effectiveness and Safety of the Aperius Perclid System vs. Standalone Decompressive Surgery in Degenerative Lumbar Spinal Stenosis With Neurogenic Intermittent Claudication 111 Table 67: Coflex, Product Status 112 Table 68: A Multicenter, Prospective, Randomized, Clinical Trial Comparing Stabilization With Coflex vs. Pedicle Screw Fixation and Fusion After Decompression for at Least Moderate Lumbar Spinal Stenosis 113 Table 69: Comparative Evaluation of Clinical Outcome in the Treatment of Degenerative Spinal Stenosis With Concomitant Low Back Pain by Decompression With and Without Additional Stabilization Using the Coflex Interspinous Implant 113 Table 70: FLEXUS Inter-Spinous Spacer, Product Status 114 Table 71: Flexus Inter-Spinous Spacer for the Treatment of Lumbar Spinal Stenosis 115 Table 72: In-Space, Product Status 115 Table 73: A Multi-Center Randomized Controlled Trial of In-Space Compared to X STOP for the Treatment of Moderate Degenerative Lumbar Spinal Stenosis 116 Table 74: Interbody Cages Market, List of Pipeline Products, Global, 2010 117 Table 75: CBK-PEEK Cervical Cage, Product Status 117 Table 76: Evaluation of the Morbidity After Cervical Fusion With an Anterior Cage on 116 Cases 118 Table 77: PCB, Product Status 119 Table 78: Anterior Cervical Spine Reconstruction Using the Titanium Plate-Cage Implant (PCB): Preliminary Results 119 Table 79: PCB - Titanium Cervical Plate-Cage Clinical Outcomes 120 Table 80: KLA-PEEK Lordotic ALIF Cage, Product Status 121 Table 81: Lumbar and Lumbo-Sacral Arthrodesis by Anterior Approach: Indications And Results of a Series of 210 Cases 121 Table 82: Pedicle Screw Systems Market, List of Pipeline Products, Global, 2010 122 Table 83: Elaspine, Product Status 122 Table 84: Elaspine Implant System Post Marketing Clinical Study: A Prospective, Multicenter Study to Evaluate the Safety and Performance of the Elaspine System in the Surgical Treatment of Degenerative Lumbar Spine 123 Table 85: G5 Posterior Screw System, Product Status 124 Table 86: HA Coated TSRH 3Dx Osteogrip Screws, Product Status 124 Table 87: OsseoFix Spinal Fracture Reduction System, Product Status 125 Table 88: Spinal Plating Systems Market, List of Pipeline Products, Global, 2010 125 Table 89: Cervical Laminoplasty Plate System, Product Status 126 Table 90: LYRA, Product Status 126

Table 91: Pioneer Anterior Cervical Plate, Product Status 126 Table 92: Spinal Surgery Devices Market, Mergers and Acquisitions, By Volume, Global, 2008–2011* 128 Table 93: Johnson & Johnson Enters Into an Agreement to Acquire Synthes, 2011 128 Table 94: Integra LifeSciences Acquires SeaSpine, 2011 130 Table 95: Alphatec Spine Completes Acquisition Of Scient'x Groupe, 2010 130 Table 96: NuVasive Acquires Cervitech, 2009 131 Table 97: Zimmer Holdings Acquires Abbott Spine from Abbott Laboratories, 2008 132 Table 98: Integra LifeSciences Holdings Acquires Theken Spine, 2008 132 Table 99: Zimmer Holdings Acquires Endius, 2007 133 Table 100: Medtronic Acquires Kyphon, 2007 134 Table 101: MiMedx Acquires SpineMedica, 2007 134 Table 102: Orthofix Acquires Blackstone Medical, 2006 135 1.2 List of Figures Figure 1: Spinal Surgery Devices Market, Global, Overall Revenue ($bn), 2010–2017 14 Figure 2: Spinal Surgery Devices Market, The US and Other Countries Contribution (%), 2010 15 Figure 3: Spinal Surgery Devices Market, Global, Company Share (%), 2010 16 Figure 4: Spinal Surgery Devices, Market segmentation 21 Figure 5: Spinal Surgery Devices Market, Global, Revenue ($bn), 2003–2010 24 Figure 6: Spinal Surgery Devices Market, Global, Revenue ($bn), 2010–2017 25 Figure 7: Spinal Surgery Devices Market, Global, Company Share (%), 2010 26 Figure 8: Spinal Surgery Devices Market, Lateral Vs Traditional Approach for Lumbar Spinal Fusion Devices 28 Figure 9: Spinal Surgery Devices Market, 3D Image Guided Spine Surgery Vs Traditional X-Rays for the Placement of Pedicle Screws 29 Figure 10: Spinal Fusion Procedures, Global, 2006–2011 30 Figure 11: Percentage of People Aged 65 Years and Above in Total Adult Population, By Country (%), 1980–2050 32 Figure 12: Spinal Surgery Devices Market, Minimally Invasive Spinal Surgery vs. Conventional Spinal Surgery 33 Figure 13: Orthopedic Surgeons by Age Group, The US, 2010 35 Figure 14: Spinal Fusion Devices Market, Global, Revenue ($bn), 2003–2010 38 Figure 15: Spinal Fusion Devices Market, Global, Revenue ($bn), 2010–2017 39 Figure 16: Spinal Non-Fusion Devices Market, Global, Revenue ($m), 2003–2010 43 Figure 17: Spinal Non-Fusion Devices Market, Global, Revenue ($m), 2010–2017 44 Figure 18: Spinal Surgery Devices Market, Spinal Fusion vs. Spinal Non-Fusion 45 Figure 19: Spinal Surgery Devices Market, The US, Revenue ($m), 2003–2010 47 Figure 20: Spinal Surgery Devices Market, The US, Revenue ($m), 2010–2017 49 Figure 21: Spinal Surgery Devices Market, Canada, Revenue ($m), 2003–2010 51 Figure 22: Spinal Surgery Devices Market, Canada, Revenue ($m), 2010–2017 52 Figure 23: Spinal Surgery Devices Market, The UK, Revenue ($m), 2003–2010 54 Figure 24: Spinal Surgery Devices Market, The UK, Revenue ($m), 2010–2017 56 Figure 25: Spinal Surgery Devices Market, France, Revenue ($m), 2003–2010 57 Figure 26: Spinal Surgery Devices Market, France, Revenue ($m), 2010–2017 59 Figure 27: Spinal Surgery Devices Market, Germany, Revenue ($m), 2003–2010 60 Figure 28: Spinal Surgery Devices Market, Germany, Revenue ($m), 2010–2017 62 Figure 29: Spinal Surgery Devices Market, Italy, Revenue ($m), 2003–2010 63 Figure 30: Spinal Surgery Devices Market, Italy, Revenue ($m), 2010–2017 65

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Spinal Surgery Devices Market, Spain, Revenue ($m), 2003–2010 66 Spinal Surgery Devices Market, Spain, Revenue ($m), 2010–2017 68 Spinal Surgery Devices Market, Japan, Revenue ($m), 2003–2010 70 Spinal Surgery Devices Market, Japan, Revenue ($m), 2010–2017 71 Spinal Surgery Devices Market, China, Revenue ($m), 2003–2010 72 Spinal Surgery Devices Market, China, Revenue ($m), 2010–2017 74 Spinal Surgery Devices Market, Australia, Revenue ($m), 2003–2010 75 Spinal Surgery Devices Market, Australia, Revenue ($m), 2010–2017 77 Spinal Surgery Devices Market, India, Revenue ($m), 2003–2010 78 Spinal Surgery Devices Market, India, Revenue ($m), 2010–2017 80 Spinal Surgery Devices Market, Brazil, Revenue ($m), 2003–2010 81 Spinal Surgery Devices Market, Brazil, Revenue ($m), 2010–2017 83 Spinal Surgery Devices, Market Opportunities and Risk Evaluation 85 Medtronic, Inc., Internal Factor Analysis, 2011 87 DePuy, Inc., Internal Factor Analysis, 2011 90 Synthes, Inc., Internal Factor Analysis, 2011 92 Stryker Corporation, Internal Factor Analysis, 2011 94 NuVasive, Inc., Internal Factor Analysis, 2011 96

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